google-site-verification=cXrcMGa94PjI5BEhkIFIyc9eZiIwZzNJc4mTXSXtGRM What is childhood dementia? How can new research help? - 360WISE MEDIA
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Health and Wellness

What is childhood dementia? How can new research help?

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“Childhood” and “dementia” are two words we’d moderately not use together. But unfortunately in the realm 1,400 Australian children and young people they live with currently incurable childhood dementia.

Generally, childhood dementia is attributable to any of those greater than 100 rare genetic diseases. Although the causes differ from dementia acquired later in life, the progressive nature of the disease is the identical.

Half infants and youngsters diagnosed with childhood dementia won’t live past their tenth birthday, and most will die before the age of 18.

However, this devastating disease has lacked the attention and, importantly, the research attention needed to develop treatments and cures.



More in regards to the reasons

Most forms of childhood dementia are so-called caused By mutations (or errors) in ours GOUT. These errors result in quite a lot of rare genetic diseases that in turn cause childhood dementia.

Two thirds dementia in children is attributable to “inborn errors of metabolism“. This signifies that the metabolic pathways involved in breaking down carbohydrates, lipids, fatty acids and proteins within the body usually are not working.

As a result, neural pathways stop working, neurons (nerve cells that send messages to the body) die, and cognitive function progressively declines.

Childhood dementia is related to rare genetic diseases.
Maxim Ibragimov/Shutterstock

What happens to children with childhood dementia?

Most babies initially appear unaffected. But after a period of apparently normal development, children suffer from childhood dementia progressively lose all previously acquired skills and skills, comparable to talking, walking, learning, remembering and reasoning.

Childhood dementia also results in significant behavioral changes comparable to aggression and hyperactivity. Serious sleep disturbances are common, and vision and hearing disturbances may additionally occur. Many children have seizures.

The age at which symptoms begin can vary, partly depending on the precise genetic disorder causing dementia, but the typical is around two years. The symptoms are attributable to significant, progressive brain damage.

Are there any treatments available?

Currently treating childhood dementia under evaluation or approved are for a really limited variety of conditions and are only available in certain parts of the world. These include: gene exchange, genetically modified cell therapy and protein or enzyme substitute therapy. Enzyme substitute therapy is available in Australia one type of childhood dementia. These therapies aim to “fix” the issues that cause the disease and have shown promising results.

Other experimental therapies include people who objective defective protein production or reduce inflammation within the brain.



There is a scarcity of research attention

Death rates of Australian children with cancer almost by half between 1997 and 2017 because of research that has enabled the event of many therapies. But in recent a long time nothing has modified for kids with dementia.

Between 2017 and 2023, pediatric cancer research received greater than 4 times the funding per patient in comparison with research funding childhood dementia. This is despite childhood dementia causing: similar variety of deaths every year as a childhood cancer.

Success for childhood cancer patients in recent a long time shows how adequate funding of medical research can result in improved patient outcomes.

An old woman holds a young girl on her lap.
Dementia is not only a disease of older people.
Miljan Zivkovic/Shutterstock

Another bottleneck for pediatric dementia patients in Australia is the shortage of access to clinical trials. Some evaluation published in March this yr found that as of December 2023, only two clinical trials in Australia were recruiting patients with childhood dementia.

However, 54 trials have been recruiting globally, meaning Australian patients and their families must watch as patients in other parts of the world receive potentially life-saving treatments without the choice of self-treatment.

That said, we have now seen a slowdown in creation Clinical tests lately worldwide within the treatment of childhood dementia.



Moreover, we all know from consultations with families current care and support systems they don’t meet needs children with dementia and their families.

New research

We were recently awarded new financing Down our research for childhood dementia. This will help us proceed and expand research to develop life-saving therapies.

More broadly, we’d like increased funding in Australia and world wide for research to develop and translate treatments for the big selection of conditions related to childhood dementia.

This article was originally published on : theconversation.com
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Health and Wellness

Biden administration postpones cigarette ban again

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Menthol Cigarettes, FDA, ban, petition

 


The Biden administration was expected to ban menthol cigarettes in March 2024, but as a substitute selected to postpone the choice indefinitely, sparking outrage and lawsuits from groups that had advocated for the ban on behalf of Black Americans.

As reported, the Biden administration, including Health and Human Services Secretary Xavier Becerra, does he tried to clarify his decision as stemming from feedback from civil rights and criminal justice groups, but this explanation has meanwhile been rejected by anti-smoking groups as stemming from political expediency slightly than public health policy.

“There has been a lot of historical interest in this rule, and the public comment period generated a tremendous amount of feedback, including from various elements of the civil rights and criminal justice movements,” Becerra said in a press release. “It is clear that there are still many conversations to be had and this will take much longer.”

Illinois Democratic Rep. Robin Kelly, chair of the Health Braintrust Congressional Black Caucus, responded to the request: Biden Administration Delay in Ruling on Menthol Cigarettes with a press release to. “I am deeply disappointed that the FDA has chosen to abandon its established plan to ban menthol cigarettes,” Kelly said. “FDA experts have clearly expressed that menthol cigarettes are harmful to public health. This is a common sense plan that could save hundreds of thousands of lives.”

Thanks largely to the efforts of Big Tobacco and the promoting industry, menthol cigarettes have develop into a fixture in promoting aimed toward the black community, which has led to black people making up nearly all of menthol cigarette smokers. This also pertains to the undeniable fact that lung cancer, the style of cancer that occurred related to cigarette smokeIs probably the most common cancer affecting black men.

In February, the N.A.A.C.P reiterated its calls for a ban on menthol cigarettes after the discharge of a study that showed that black voters overwhelmingly supported the FDA’s proposed ban on menthol cigarettes. In a press release, NAACP President and CEO Derrick Johnson called on the Biden administration to place people over politics.

“This new data confirms what we already know to be true – black voters want a menthol ban. It’s time for the Biden administration to put people before profits and quickly enact a policy that will save countless Black lives. We’re done waiting. The NAACP will continue to do everything in its power to hold this administration accountable to its promises to our community. Enough. Our lives are at risk.”

Also in February this 12 months The American Heart Association issued a press release including a call from two former U.S. surgeons general for the Biden administration to just accept the FDA’s proposed ban on menthol cigarettes. Regina Benjamin and Jerome Adams wrote a joint column for and noted the tobacco industry’s efforts to achieve specific demographic groups. “As surgeons general under both Republican and Democratic administrations, we have consistently called attention to the enormous toll of tobacco use, highlighted the vast health disparities that continue to ravage Black and minority communities, and emphasized evidence-based measures to address reducing smoking rates and saving lives,” Benjamin and Adams wrote.

The pair concluded: “We strongly believe that in order to protect public health, menthol cigarettes and flavored cigars should no longer be sold. We urge the Biden administration not to be distracted by the tobacco industry and its apologists. Instead, the administration should act in the interests of children, families and communities.”

This article was originally published on : www.blackenterprise.com
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Health and Wellness

A tax on sugary drinks could make us healthier. It’s time for Australia to introduce one

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Sweet drinks cause weight gain and increase the danger quite a few diseases, including diabetes.

The the evidence shows that well-designed taxes can reduce sales of sugary drinks, push people to select healthier options, and prompt manufacturers to reduce the sugar content of their drinks. And although these taxes have only been in place for a brief time, there are already signs that they’re making people healthier.

It’s high time Australia caught up with the remainder of the world and introduced a tax on sugary drinks. As our latest Grattan Institute report because it shows, this could mean the common Australian drinks almost 700 grams less sugar a yr.

Sweet drinks make us sick

Since 1980, the share of adults in Australia affected by obesity has tripled, from 10% to over thirty%and diabetes is ours the fastest growing chronic condition. The costs to the health care system and the economy are measured in billions of dollars every year. However, the best costs are borne by individuals and their families in the shape of illness, suffering and premature death.

Sugary drinks are a giant a part of the issue. The more we drink, the greater the danger of their occurrence put on weight, development of type 2 diabetesand suffering poor oral health.

These drinks contain no nutrients but are high in sugar. The average Australian consumes it 1.3 times the utmost really useful amount of sugar per day. Sugary drinks account for greater than 1 / 4 of our day by day sugar intake, greater than every other major food.

You could also be shocked by the quantity of sugar you drink. Many 375 ml cans of sentimental drinks contain 8 to 12 teaspoons of sugar, which is nearly your complete really useful day by day limit for an adult. Many 600 ml bottles blow our entire day by day sugar budget after which some.

600 ml of a soft drink exceeds the really useful day by day limit.
Grattan Institute

The situation is even worse for disadvantaged Australians, who’re more vulnerable to this example diabetes AND obesityand who also devour probably the most sugary drinks.

Taxes on sugary drinks work

Fortunately, there may be a proven way to reduce the damage attributable to sugary drinks.

More than 100 countries introduce a tax on sugary drinks covering nearly all of the world’s population. Tests shows that these taxes lead to higher prices and fewer purchases.

Some taxes are intended to encourage manufacturers to change recipes and reduce the sugar content of their drinks. Under these “tiered taxes” there is no such thing as a tax on low-sugar drinks, however the tax increases by two or thrice as the quantity of sugar increases. This gives producers a robust incentive to add less sugar, thereby reducing their exposure to the tax or avoiding it altogether.

This is one of the best results of introducing a tax on sweetened drinks. This means drinks grow to be healthier and tax is kept to a minimum.

Soft drinks in the store refrigerator
Manufacturers have an incentive to use less sugar.
Erik Mclean/Pexels

In countries with tiered taxes, manufacturers have reduced the sugar content of their drinks. In the UK, the share of products exceeding the tax threshold dropped dramatically. In 2015, over half (52%) of products within the UK exceeded the tax threshold of 5 grams of sugar per 100 ml. Four years later, when the tax was in force, this share dropped to 15%. The variety of products containing probably the most sugar – over 8 grams per 100 ml – dropped probably the most, from 38% to just 7%.

The Australian drinks market today looks similar to the UK before the tax was introduced.

As you possibly can see within the third chart, the sugar content in drinks within the UK dropped dramatically after the introduction of the tax.
Grattan Institute

The health advantages take time to materialize, but there are already encouraging signs that taxes are working. Obesity amongst school-age girls has decreased Great Britain AND Mexico.

Oral health has also improved, with studies showing that fewer children go to hospital for tooth extraction Great Britainand reducing tooth decay in Mexico AND Philadelphia.

One research from the United States found a big reduction within the incidence of gestational diabetes in cities with a tax on sugary drinks.

A tax Australia should introduce

Similar to effective taxes abroad, Australia should introduce a sugary drinks tax that can goal drinks that contain probably the most sugar:

  • Beverages containing 8 grams or more of sugar per 100 ml ought to be subject to a tax of $0.60 per liter
  • drinks weighing 5-8 grams ought to be taxed at $0.40 per liter
  • drinks containing lower than 5 grams of sugar ought to be tax-free.

This implies that 250 ml of Coke, which accommodates almost 11 grams of sugar per 100 ml, will cost $0.15 more. But in fact consumers could avoid the tax by selecting a sugar-free soft drink or bottle of water.

Grattan Institute modeling shows that under this tiered tax, Australians would drink around 275 million liters less of sugary drinks a yr, equivalent to the amount of 110 Olympic swimming pools.

A man looks at the label of a drink
The more sugar, the upper the tax ought to be.
Teguh Sugi/Pexels

The tax concerns health, but government budgets also profit from it. If launched today, it will raise about half a billion dollars in its first yr.

Interest groups akin to the beverage industry fiercely oppose taxes on sugary drinks world wide, issuing disingenuous warnings in regards to the risks to poor people, the sugar industry and beverage producers.

However, our latest report shows that taxes on sugary drinks have been implemented successfully overseas and none of those concerns should hold Australia back.

We definitely cannot rely on industry guarantees to voluntarily reduce sugar consumption. They were weak and misleading and failed to stick.

Many policies and interventions are needed to reverse the tide of obesity and chronic disease in Australia, but a tax on sugary drinks ought to be a part of the answer. It’s a policy that works, is simple to implement and applies to nearly all of Australians Support it.

The federal government should show it’s serious about solving Australia’s biggest health problems and take this small step towards a healthier future.

This article was originally published on : theconversation.com
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Health and Wellness

7 creative tequila cocktails for Cinco De Mayo

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(*7*)

Plane

Happy Cinco de Mayo! It’s time to rejoice. What higher solution to toast to a spirited holiday than with unique and attractive tequila cocktails? To enable you to entertain your guests, we have prepared seven craft cocktails and recipes for you to try. We’ve got the whole lot for you, from classic margaritas to Sunrise tequila and Paloma!

Scroll all the way down to take notes.

classic margarita: :

Kick off your Cinco de Mayo celebration with a timeless classic – the margarita! Mix a batch of margaritas using DeLeón Blanco tequila, fresh lime juice and triple sec. Shake with ice, strain into glasses with salt and garnish with a lime wedge for a refreshing and spicy cocktail that your guests are sure to enjoy.

DeLeón Paloma: :

Give the classic Paloma cocktail a twist through the use of DeLeón Blanco Tequila as the bottom spirit. Combine tequila with grapefruit soda, fresh lime juice and a splash of sparkling water for a sparkling and citrusy refreshment perfect for sipping on a hot Cinco de Mayo afternoon. Serve over ice with a slice of grapefruit for extra flavor.

Sunrise with Tequila: :

Brighten up your Cinco de Mayo celebrations with a vibrant Tequila Sunrise cocktail made with DeLeón Blanco tequila. Place tequila, orange juice and grenadine in a glass for a shocking sunrise effect. Garnish with an orange slice and a cherry for a visually stunning cocktail that tastes pretty much as good because it looks.

Spicy Margarita: :

Add some warmth to your Cinco de Mayo celebration with a spicy margarita made with DeLeón Blanco tequila. In a shaker, crush jalapeño slices with fresh lime juice, then add tequila, triple sec and ice. Shake well, strain right into a glass with ice and garnish with a jalapeño slice for an additional boost of flavor. This fiery cocktail will certainly boost your fiesta!

Additional recipes:

Watermelon Margarita

Ingredients

  • 2-piece Cristalino reserve plane
  • 2 parts fresh lime juice
  • 2 parts crushed watermelon slices
  • 1 part agave nectar
7 creative tequila cocktails for Cinco De Mayo

Preparation

  • Cut the watermelon pulp into small cubes and add to the blender. Mix until smooth.
  • Then take a shaker and add ice cubes, followed by 2 ounces of premium Avión Silver tequila, fresh lime juice and agave nectar.
  • Shake vigorously for about 10-15 seconds.
  • Then strain the mixture through a nice strainer over the blended watermelon juice in a glass stuffed with ice cubes.
  • Mix well to mix all of the flavors.
  • For an additional boost of flavor, add just a little salt to the rim of your glass before pouring your cocktail.
  • Decorate with watermelon slices

Sour plane

Ingredients

  • 1.5 parts Reserve plane 44
  • ½ part lemon juice
  • 1 part orange juice
  • 1 fresh egg white
  • ¼ a part of agave syrup
  • Orange peel for decoration
  • Edible flowers for decoration
7 creative tequila cocktails for Cinco De Mayo

Preparation

  • In a cocktail shaker, add all ingredients
  • Put the lid on and shake dry without ice for about 20 seconds.
  • Add ice and shake again for about 20 seconds.
  • Strain right into a coupe glass and decorate with edible flowers.

Filtered Clear Margarita

Ingredients

  • 1 ½ parts of the Cristalino reserve plane
  • 1 part filtered lime juice
  • 1 a part of sugar syrup
  • ice
7 creative tequila cocktails for Cinco De Mayo

Preparation

  • Add one and a half ounces of Avión Reserva Cristalino, filtered lime juice, and straightforward syrup to a shaker.
  • Then give attention to technique. Shaking all of the ingredients along with ice will create air bubbles within the mixture, which can cloud the looks when poured right into a glass. Instead, stir gently until thoroughly mixed and punctiliously strain through a fine-mesh strainer.
  • Strain through a coupette glass.
  • Garnish with a slice of lime.
  • Remember to only use clear ice cubes and omit any fruit juices that would add color.

This article was originally published on : www.essence.com
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