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In the USA, bird flu was detected in pigs. Why does this matter?

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Last week, the U.S. Department of Agriculture reported that a pig at a backyard farm in Oregon had been infected with bird flu.

As the bird flu situation continues to evolve, now we have learned that the A/H5N1 strain of the virus infects a spread of animals, including quite a lot of birds, wildlife and dairy cattle.

Fortunately, now we have not seen sustained spread of the virus between people at this stage. However, the detection of the virus in pigs represents a worrying development in the trajectory of this virus.

How did we get here?

The most concerning sort of bird flu currently circulating is clade 2.3.4.4b A/H5N1, the influenza A strain.

Since 2020, the A/H5N1 2.3.4.4b virus has spread to a big selection of birds, wildlife and livestock which have never previously been infected with avian influenza.

While Europe is a hotspot for A/H5N1, attention is currently focused on the US. In 2024, dairy cattle were infected for the first time, with over The problem affects 400 herds in a minimum of 14 US states.



Bird flu has huge consequences for breeding and industrial food production, as infected poultry flocks should be slaughtered and infected cows may result in contamination dairy products. That said, pasteurization should make the milk secure to drink.

Although farmers have suffered heavy losses as a consequence of H5N1 bird flu, it may well also mutate to cause a pandemic in humans.

Birds and humans have various kinds of receptors in their respiratory tract to which influenza viruses attach, corresponding to a lock (receptors) and a key (virus). The attachment of the virus allows it to enter the cell and body and cause disease. Avian influenza viruses are adapted to birds and spread easily amongst birds but not in humans.

So far, human cases have mainly occurred in individuals who stayed at the facility close contact with infected livestock or birds. In the US, the majority were agricultural employees.

The fear is that the virus will mutate and adapt to humans. One key step for this to occur could be to vary the virus’s affinity from bird receptors to receptors found in the human respiratory tract. In other words, if the virus “key” has mutated to raised fit the human “lock”.

Recent testing of sample A/H5N1 2.3.4.4bz infected person, disturbing results were obtainedidentifying mutations in the virus which will increase transmission between human hosts.

Why are pigs an issue?

A pandemic strain of influenza in humans can arise in several ways. One involves close contact between humans and animals infected with their very own specific influenza viruses, creating opportunities mixing of genes of avian and human viruses.

Pigs are the perfect vessel for mixing genes to supply a human strain of pandemic flu because they’ve receptors in their respiratory tract that each avian and human influenza viruses it may well get tied up.

This signifies that pigs will be infected with each avian influenza virus and human influenza virus. These viruses can exchange genetic material, mutate and simply transmit to humans.


Conversation, CC BY-SA

Interestingly, there have been pigs in the past less vulnerable to A/H5N1 viruses. However, the virus has recently mutated they infect pigs more easily.

In a recent case in Oregon, A/H5N1 was detected in a pig on a non-commercial farm following an outbreak of disease amongst poultry kept on the same holding. This A/H5N1 strain originated from wild birdsand never the one common in US dairy cows.

Pig infection is a warning. If the virus makes its way into industrial piggeries, it might create a much higher level of pandemic risk, especially as winter approaches in the U.S., when seasonal human flu cases begin to extend.



How can we minimize the risk?

Surveillance is vital to early detection of a possible pandemic. This includes comprehensive testing and reporting of infections in birds and animals financial compensation and support measures for farmers to encourage timely reporting.

Strengthening global surveillance of influenza is crucial because unusual spikes in pneumonia and severe respiratory illnesses could signal a human pandemic. Our EPIWATCH system looks for early warnings of such activity, which can accelerate vaccine development.

If a cluster of human cases occurs and influenza A is detected, further testing (called subtyping) is vital to find out whether it’s a seasonal strain, an avian strain resulting from transmission of the virus, or a brand new pandemic strain.

Early identification can prevent a pandemic. Any delay in identifying an emerging pandemic strain allows the virus to spread widely across international borders.

The first human case of A/H5N1 in Australia was in a baby who became infected while traveling in India and was hospitalized for the disease in March 2024. Tests then identified influenza A (which might have been seasonal influenza or bird flu), but subtype to discover A/H5N1 was delayed.

This sort of delay may very well be costly if human-borne A/H5N1 emerges and is taken into account seasonal influenza because the influenza A test is positive. 5% of positive tests for influenza A undergo further subtyping in Australia and most countries.

In light of the current situation, there needs to be a low threshold for subtyping influenza A strains in humans. Rapid tests that may tell the difference between seasonal flu and H5 A flu are emerging and may form a part of governments’ pandemic preparedness.

The risk is higher than ever before

The U.S. Centers for Disease Control and Prevention states that the current risk posed by H5N1 to the general public stays low.

However, with the H5N1 virus already in a position to infect pigs and showing worrying mutations in adapting to humans, the risk level has increased. Given that the virus is so common amongst animals and birds, the statistical probability of a pandemic is higher than ever before.

The excellent news is that we’re higher prepared for a flu pandemic than other pandemics because vaccines will be produced in the same way as seasonal flu vaccines. Once the genome of the pandemic flu virus is understood, vaccines will be updated to match it.

Partially matched vaccines and a few are already available countries corresponding to Finland vaccinate high-risk farm employees.

This article was originally published on : theconversation.com
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Health and Wellness

Recipe for change: eliminating health disparities and economic empowerment – the essence

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Via Griffin/Getty Images

Throughout the 12 months, the Global Black Economic Forum held quite a few select conversations focused on solutions to the most pressing economic and social issues facing marginalized communities. One of those issues – too often missed – is the link between Black health and wealth. If we do not start eliminating health disparities and inequalities today, we cannot give you the chance to construct wealth for the future.

This intersection was the focus of an event we hosted in August as a part of our cooking talk series. It was held on Martha’s Vineyard, round the corner National Medical Scholarships (NMF), the Black World Economic Forum had the opportunity to satisfy with NMF’s unapologetic leader, Michellene Davis. Recognized by Modern Healthcare magazine as certainly one of the 25 most influential minority leaders in healthcare, Michellene’s profession has involved policy advocacy and social change.

Her organization is devoted to increasing the variety of Black, Indigenous and physicians of color through fellowships, service-learning programs, mentoring opportunities and clinical research leadership training.

The conversation revealed two easy and interconnected data points: In the next decade, the United States will experience:huge shortage of doctors while becoming a majority non-white nation. These two trends highlight the need for greater diversity on this field. Studies have shown that patients of color see racially and ethnically diverse physicians. Treatment results are frequently higher.

However, the percentage of black doctors in the US is growing at an alarmingly slow rate – it has only increased by 4% over the last 120 years.. In the face of conservatives’ regressive and destructive attacks on diversity, equity, and inclusion efforts, there has never been a greater need for us to redouble these efforts. The more we are able to improve health outcomes, the higher we’ll give you the chance to seize and compete for economic opportunities in the future. Given the urgent need to deal with health care workforce disparities and their direct impact on Black economic outcomes, it’s equally essential to acknowledge the broader economic opportunities that may drive wealth creation in our communities.

The competition for certainly one of the best economic opportunities in the history of tourism and hospitality – the 2026 FIFA World Cup – was the focus of our other curated conversation. Organized round the corner East Point Congress and Visitors Bureau, we sat down with its president, Chantel Francois. In her position, she is responsible for the development of the tourism industry in the city of East Point, Georgia. Previously, she led economic development and tourism promotion efforts in Atlanta, Trinidad and Tobago.

Francois described how local businesses run by entrepreneurs of color can leverage global events like the FIFA World Cup to extend their brand visibility, increase sales, and even start their very own businesses. She emphasized the importance of partnerships with event organizers, teams and athletes in constructing company awareness. This cooperation can also be crucial as the city government works with many stakeholders to make sure the safety of tourists and maximum economic opportunities for the area people.

When it involves such major events, it is usually essential to instill a way of community pride in each sector wherein an organization competes. This pride translates into a robust bond with travelers that may make them proceed to interact with small businesses or spark curiosity in them to learn more about the community. The 2026 FIFA World Cup has the potential to place tens of millions of dollars into the pockets and communities of individuals of color, and it’s crucial for businesses to begin planning now in the event that they have not already.

This article was originally published on : www.essence.com
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Health and Wellness

Phenergan for children under 6 years of age is currently banned due to fear of hallucinations. Here’s what you can use instead

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The Australian Drugs Regulatory Authority has issued an order safety warning over Phenergan and related products containing the antihistamine promethazine.

The Therapeutic Goods Administration has stated that over-the-counter products mustn’t be given to children under six years of age due to concerns about serious unwanted effects similar to hyperactivity, aggression and hallucinations. Breathing may additionally change into slow or shallow, which can be fatal.

When high doses are administered to young children, difficulties in learning and understanding, including reversible cognitive deficit and mental disability, may additionally occur. – said the TGA.

The latest warning follows international and Australian concerns concerning the drug in young children, which is commonly used to treat conditions similar to hay fever and allergies, motion sickness and for short-term sedative effects.

What is promethazine?

Promethazine is a “first generation” antihistamine that has been sold over-the-counter in Australian pharmacies for a long time for a spread of conditions.

Unlike many other drugs, first-generation antihistamines can cross the blood-brain barrier. This means they affect your brain chemistry, making you feel drowsy and sedated.

In adults, this will likely be useful for sleep. However, in children, these drugs can cause serious unwanted effects on the nervous system, including those mentioned on this week’s safety alert.

We’ve known about this for a while

We have known concerning the serious unwanted effects of promethazine in young children for a while.

Advice regarding 20 years ago In the United States, the drug was not beneficial for use in children under two years of age. In 2022, an Australian Medicines Advisory Committee made its own suggestion to increase the age to six. New Zealand released similar warnings and advice in May this yr.

Over the last ten years, 235 cases of serious unwanted effects from promethazine have been reported in each children and adults reported to the TGA. Of the 77 deaths reported, one was a toddler under six years of age.

Reported unwanted effects in each adults and children included:

  • 13 cases of accidental overdose (leading to 11 deaths)
  • eight cases of hallucinations
  • seven cases of slow or shallow respiration (leading to 4 deaths)
  • six cases of decreased consciousness (leading to five deaths).

TGA security alert comes after an internal investigation by the manufacturer of Phenergan, Sanofi-Aventis Healthcare. This investigation was initiated in 2022 advice from the Medicines Advisory Committee. The company has now updated its information for consumers and healthcare professionals.

What can you use instead?

If you have allergies or hay fever in young children, non-sedating antihistamines similar to Claratine (loratadine) or Zyrtec (cetirizine) are preferred. They provide relief without the chance of sedation and other disturbing unwanted effects of promethazine.

If symptoms of a chilly or cough occur, parents must be reassured that these symptoms will normally subside with time, fluid intake, and rest.

Saline nasal sprays, adequate hydration, a humidifier or elevating the kid’s head can relieve the congestion related to hay fever. Oral products containing phenylephrine marketed for nasal congestion must be avoided because evidence shows that this is the case This article was originally published on : theconversation.com

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7 things you can do if you think you’re sweating too much

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Sweating is a way for the body to chill down, a bit like an internal air conditioner.

When your body temperature rises (since it’s hot outside or you exercise), sweat glands throughout your skin secrete a watery fluid. When the liquid evaporates, it takes heat with it, protecting us from overheating.

But sweating can vary from individual to individual. Some people could get a bit of dew under their arms, others may feel like they may fill a swimming pool (perhaps not as dramatically, but you get the thought).

So what’s a traditional amount of sweat? And what’s too much?

Why do some people sweat greater than others?

How much you sweat depends upon many aspects aspects including:

The average person sweats at a rate of approx 300 milliliters per hour (at a temperature of 30°C and humidity of roughly 40%). However, because you can’t measure the quantity of your individual sweat (or weigh it), doctors use a unique measure to evaluate the impact of sweating.

They ask if sweating interferes with on a regular basis life. Maybe you stop wearing certain clothes due to sweat stains or you feel embarrassed, so you don’t go to social events or work.

If so, it’s a so-called disease state excessive sweatingwhat affects tens of millions of individuals everywhere in the world.

As you might expect, people affected by this condition most frequently report problematic underarm sweating. However, sweaty hands, feet, scalp and groin might also be an issue.

Excessive sweating could also be a symptom of one other disease, e.g hyperthyroidism, fever or menopause.

But excessive sweating cannot have an obvious cause, and the causes of this so-called primary hyperhidrosis are somewhat mysterious. People have a traditional variety of sweat glands, but scientists consider they simply produce excessive amounts of sweat when exposed to triggers reminiscent of stress, heat, exercise, tobacco, alcohol and spicy spices. There might also be a genetic link.

Okay, I’m sweating loads. What can I do?

1. Antiperspirants

Antiperspirants, especially those with aluminumThey are the primary line of defense and have been designed to scale back sweating. Deodorants only stop unpleasant body odor.

Aluminum chloride, hexahydrate, aluminum chloride or weaker tetrachlorohydrex aluminum and zirconium glycinate they react with sweat gland proteins to form a plug. This plug temporarily blocks the sweat ducts, limiting the quantity of sweat reaching the skin’s surface.

These products may contain as much as 25% aluminum. The higher the proportion, the higher these products work, however the more they irritate the skin.

Make sure you buy antiperspirant, not deodorant.
Okrasiuka/Shutterstock

2. Beat the warmth

This could seem obvious, but staying calm can make an enormous difference. This is because you have less heat to lose, which causes your body to provide less sweat.

Avoid highly regarded and long showers (you’ll have more heat to lose), wear loose clothing fabricated from breathable fabrics reminiscent of cotton (this can help sweat evaporate more easily), and carry a small hand-held fan to assist your sweat evaporate.

When exercising, try it ice bandanas (ice wrapped in a shawl or cloth after which applied to the body) or wet towels. They can be worn across the neck, head or wrists to lower body temperature.

Also try to switch when or where you exercise; If possible, try to seek out cool shade or air-conditioned places.

If your sweating remains to be affecting your life after taking the primary two steps, consult with your doctor. They will help you find the most effective strategy to cope with this problem.

3. Medicines

Some medicines may help regulate sweating. Unfortunately, a few of them can also cause uncomfortable side effects reminiscent of dry mouth, blurred vision, abdominal pain or constipation. So consult with your doctor about what’s best for you.

Your GP might also refer you to a dermatologist – a health care provider like me who makes a speciality of skin conditions – who can recommend a wide range of treatments, including among the following.

4. Botulinum toxin injections

Botulinum toxin injections usually are not used solely for cosmetic reasons. They have many applications in medicine, including: they block the nerves that control the sweat glands. They do this for months.

The dermatologist normally gives injections. But they’re only subsidized by Medical care in Australia under the arms and if you suffer from primary hyperhidrosis that can not be controlled with the strongest antiperspirants. These injections are given as much as thrice a yr. It just isn’t subsidized within the case of other diseases, e.g. hyperthyroidism or other areas, e.g. face or hands.

If you don’t qualify, you can get these shots privately, but it would cost you a whole bunch of dollars for treatment that can last as long as six months.

A healthcare worker giving a man a Botox injection under his arm
In some cases, injections can be found under Medicare.
Satyrenko/Shutterstock

5. Iontophoresis

This involves using a tool that passes a weak electric current through water to the skin decreased sweating in your hands, feet or armpits. Scientists aren’t sure how exactly it really works.

But it’s the one way to manage sweating within the hands and feet, which doesn’t require drugs, surgery or botulinum toxin injections.

This treatment just isn’t subsidized by Medicare and never all dermatologists provide it. However, you can buy your individual device and use it, which is frequently cheaper than using it privately. You can ask your dermatologist if that is the proper option for you.

6. Surgery

There is a procedure where the nerves within the hands are cut, which prevents them from sweating. This is very effective however it may cause sweating somewhere else.

There are also other surgical options that you can talk to your doctor.

7. Microwave therapy

This is newer treatment which stimulates the sweat glands to destroy them in order that they can now not work. This just isn’t quite common yet and is kind of painful. It is out there privately in several centers.

This article was originally published on : theconversation.com
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