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RSV is linked to childhood asthma – but we can’t yet say one causes the other

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As winter approaches in Australia, respiratory viruses are in all places. One of the important culprits is the RSV virus, which has caused over 145,000 infections across the country this yr. Most of them are amongst children under five.

RSV is the leading reason for bronchiolitis and pneumonia (each chest infections) in young children. Every yr no less than one in 200 children children under five are hospitalized with RSV in Australia. Babies lower than six monthsand particularly children under three months of age, are most in danger.

The RSV virus infects respiratory tract and lungswhich causes the mucus in the respiratory tract to turn into very sticky. Young children may experience coughing, wheezing, difficulty respiratory and feeding problems.

Studies indicate that severe RSV infection in infancy can also increase the risk children with asthma. So what evidence is there linking RSV to asthma? And why might this link exist?

Relationship or cause-and-effect relationship?

Asthma is a chronic lung disease that affects: 11% Australians. People with asthma often have difficulty respiratory, coughing, and wheezing. This happens because their airways turn into temporarily narrower, often due to triggers (for instance, viral infections, dust, or pollen). Asthma often begins as wheezing in preschool. But for some people, it begins in maturity.

When we speak about RSV and asthma, it is essential to consider the differences between association and causation. An association occurs when two events often occur together (for instance, smoking and drinking coffee), while a causal relationship occurs when we know that one may cause the other (for instance, smoking and lung cancer). While the association between RSV and asthma is well-established, a causal relationship it has not been proven yet.

To prove a causal relationship, certain criteria should be met. These include a temporal relationship (on this case, RSV infection must occur before asthma) and a plausible explanation (a biological mechanism).

Infants are at biggest risk of RSV infection.
Gorodenkoff/Shutterstock

Some evidence suggests that RSV infections change the developing cells in the airways of infants and young children. This could mean that the protective or barrier function of the lining of the airways is altered, predisposing a toddler to turn into sensitized to allergens — when their immune system makes antibodies to something they encounter, similar to grass or dust.

Allergen sensitization is a major risk factor for asthma, so severe RSV infection may contribute to the development of asthma through sensitization to common environmental allergens. This is a possible biological mechanism, but we still need more research to confirm this.

Several studies show an association between severe RSV infection and recurrent wheezing and asthma in later childhood.

But what comes first? one studyChildren under 12 months of age who developed RSV bronchiolitis were followed for six years. Almost half (48%) were diagnosed with asthma before their seventh birthday.

Similarly in one other testChildren hospitalized for RSV infection before the age of two were more likely to develop asthma by the age of 18 than those that weren’t hospitalized.

However, the researchers who conducted twin study concluded that the data were more likely to indicate reverse causation. That is, children with a predisposition to asthma were more likely to develop RSV requiring hospitalization.

Father helps smiling boy breathe through nebulizer.
Asthma often begins in preschool age.
Kleber Cordeiro/Shutterstock

We could also be closer to the answer

The pendulum could also be swinging towards causality. Recent findings from South Africa Birth Cohort Study showed that severe RSV infections were related to each recurrent wheezing and subsequent impairment of lung function.

Some prior examination Studies conducted by this group showed that hospitalization for any respiratory infection, and particularly for RSV, was related to recurrent respiratory infections and wheezing. Recurrent wheezing and decreased lung function are predictors of future asthma.

Other last examination Studies of greater than 1,700 children in the United States have shown that avoiding RSV infection in infancy can prevent up to 15% of childhood asthma cases.

Recently, the possibility of vaccinating moms and using monoclonal antibodies to prevent RSV infection has emerged, which is able to probably help answer this query once and for all.

Earlier this yr, nirsewimab (a long-acting monoclonal antibody) became available for infants and young children through state programs in Western Australia, Queensland AND New South Wales. Nirsevimab works barely in another way than the vaccine, but is similarly administered as an injection.

In addition, the RSV vaccine Abrysvo was licensed in Australia this yr to be used while pregnant to protect the baby after birth. It is available to pregnant women to buy privately on prescription from a health care provider, while South Australia recently announced it is going to provide Abrysvo free to pregnant women next yr.

With these measures, hopefully we will see a discount in RSV at a population level in the coming years. If we see a discount in asthma at the same time, this will likely finally answer the query of causality.

A nurse talks to a pregnant woman.
A vaccine against the RSV virus has already been registered for pregnant women.
MilanMarkovic78/Shutterstock

Protecting children and communities

Although it is still not known whether RSV causes asthma, RSV and other viral infections will be especially problematic for individuals who have already got asthma. In each cases adults in children with asthma, respiratory diseases of viral origin can have a more severe course and cause an exacerbation asthma symptoms.

RSV It is spread through coughing, sneezing, and shut contact. There are many other viruses that spread in similar ways. Parents will help keep their children and others healthy by encouraging children to cover their mouths and noses when coughing or sneezing and to wash their hands recurrently.

Ensuring that children don’t go to school, daycare, or other children once they are sick helps prevent the spread of many viruses, including RSV. Finally, staying up to date on vaccinations and getting a flu shot yearly could make an enormous difference in our health and the health of those around us.

This article was originally published on : theconversation.com
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Health and Wellness

More than half of party drug users take ADHD medication without a prescription, new study finds

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Each 12 months, the National Drug and Alcohol Research Centre on the University of New South Wales in Sydney surveys a whole bunch of regular drug users in Australia to seek out out understand trends within the use of psychoactive substances throughout the country.

Today we published Report 2024during which 740 people from Australian capital cities who usually use ecstasy or other illegal stimulants were surveyed.

While the first focus of our research is illicit drugs and markets, we also monitor trends within the over-the-counter use of pharmaceutical stimulants, resembling ADHD medications.

This 12 months, 54% of people we spoke to had used pharmaceutical stimulants previously six months after they weren’t prescribed them, the best percentage now we have seen since we began asking people about this kind of drug use in 2007.

What are pharmaceutical stimulants?

Pharmaceutical stimulants include the drug methylphenidate (trade names Concerta and Ritalin), in addition to dexamfetamine and lisdexamfetamine (Vyvanse).

These medications are commonly prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsya chronic neurological disorder that causes excessive sleepiness and sudden sleep attacks through the day.

These drugs work in other ways depending on the kind. However, they treat ADHD by increasing levels of necessary chemicals (neurotransmitters) within the brain, including dopamine and norepinephrine.

However, as with many pharmaceutical substances, people also use these stimulants after they should not prescribed. There is range of reasons someone may select to make use of these medications without a prescription.

Tests University students have shown that these substances are sometimes used to extend alertness, concentration and memory. Studies conducted amongst wider populations have shown that they may also be used experimentor to get high.

All over the world, including in Australiawere significant increases within the prescription of ADHD medications lately, likely on account of increased identification and diagnosis of ADHD. As prescriptions increase, the danger of these substances being diverted to illegal drug markets increases.

Some people may seek pharmaceutical stimulants to extend alertness and concentration.
Ground Photo/Shutterstock

What we found

The percentage of people using stimulants without a prescription has tripled since monitoring began – from 17% of respondents in 2007 to 54% in 2024. It has remained at a similar level lately (52% in 2022 and 47% in 2023).

Frequency of use remained relatively low. Respondents typically reported using non-prescribed pharmaceutical stimulants monthly or less continuously.

In this study, participants most continuously reported using dexamfetamine, followed by methylphenidate and lisdexamfetamine. Most (79%) said it was “easy” or “very easy” to acquire these substances, just like 2022 and 2023.

Of course, provided that our study focused on regular drug users, the over-the-counter use of pharmaceutical stimulants doesn’t reflect their use in the final population.

In 2022–2023 National Household Drug Strategy Surveygeneral population survey of Australians aged 14 years and over, 2.1% of the population (comparable to about 400,000 people) reported using pharmaceutical stimulants for non-medical purposes within the previous 12 months. This was just like the proportion of people reporting using ecstasy.

What are the risks?

Pharmaceutical stimulants are considered to have a relatively secure toxicity profile. However, like all stimulants, these substances increase activity sympathetic nervous systemwhich controls various functions within the body during times of stress. This in turn increases heart rate, blood pressure and respiration rate.

These changes may cause acute cardiac events (resembling arrhythmias or irregular heartbeats) and, with repeated use of high doses, chronic changes in heart work.

Recent Australian research has documented increase in poisoning involving these substances, although a significant proportion of these seem like intentional poisonings. In the poisonings that involved only pharmaceutical stimulants, the drugs were mostly taken orally, with the median dose being more than ten times the everyday prescribed dose. The commonest symptoms were hypertension (hypertension), tachycardia (fast heart rate), and agitation.

In our study, individuals who took pharmaceutical stimulants most frequently took them in pill form, taking a dose barely higher than that typically prescribed.

However, about one in 4 people reported snorting as a route of administration. This can lead to physical harm, resembling damage to the sinuses, and will increase the potential risks of the drug because it will possibly come into effect faster within the body.

A hand holds a bag of white powder.
Snorting stimulants could also be more dangerous.
Author: DedMityay/Shutterstock

Some pharmaceutical stimulants are “long-acting,” released into the body throughout the day. So there may additionally be a risk of premature re-dosing if people unknowingly use these preparations more than once a day. That is, if people don’t experience desired effects They may take one other dose on the expected time, which can increase the danger of uncomfortable side effects.

Finally, non-prescribed stimulants can have negative effects when taken with other medications. This can include a “masking effect” (for instance, a stimulant may mask the symptoms alcohol poisoning).

So what should we do?

Pharmaceutical stimulants are necessary medications within the treatment of ADHD and narcolepsy, and when used as directed, they’re relatively secure. However, there are additional risks when people use these substances without a prescription.

Harm reduction campaigns that highlight these risks, including differences between formulations, will be useful. Ongoing monitoring, alongside more in-depth investigation of associated harms, can also be key.

This article was originally published on : theconversation.com
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Health and Wellness

Usher’s Groomer Shares His Skin Care Routine That Keeps Him in Shape at 45

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Kevin Mazur/Getty Images

Shortly after Labor Day, the consummate entertainer Usher played 4 consecutive sold-out shows in Brooklyn, New York, as a part of his . For two hours each night, he danced, sang, poured drinks for fans (you only needed to be there), and partied with special musical guests, all while his skin glowed. And not simply because he was sweating, although he was sweating loads. But also since the star, who has been around for 3 many years, has flawless skin at age 45. How does he do it?

With proper skincare and the assistance of hairdresser, Lola Okanlawon.

I had the chance, together with a gaggle of journalists and public opinion influencers, to hearken to the speech of Okanlawon, a famous make-up artist and licensed dermatologist DiAnne Davis, MDconcerning the tricks to having an unparalleled skincare routine, and all of it revolves around the suitable products. In addition to dancing with Usher, our presence that evening was also to have a good time the launch of a skincare brand Ceravelatest Eye cream with skin renewing vitamin Cwhich joins their popular Skin Renewing line. Usher uses it, and Davis says it’s best to too.

“Their whole Skin Renewing line really helps target some of the things that you might start to notice as you get a little older,” the plastic surgeon and skincare expert shared. “So maybe you’ve lost a little elasticity, or maybe your skin tone isn’t even, or maybe you’ve noticed a few fine lines and wrinkles here and there. That’s what this Skin Renewing line is all about.”

The key ingredients of the brand new eye cream are hyaluronic acid, which moisturizes, ceramides, which protect and moisturize the skin, caffeine, which reduces puffiness under the eyes, and five percent vitamin C, which brightens the skin across the eyes without irritating it.

(*45*) she says.

Okanlawon visited the artist before ending Usher’s pre-concert styling and opened up about her collaboration with the star, with whom she has been in a relationship for 3 years.

“I take care of all of his skin, from head to toe,” she told us, noting that they’re each fans of Cerave, which she uses often to prep him for the cameras and the massive stage.

“It’s important to have a skin prep routine before you go on stage. This man doesn’t play with his skin or his body,” she shared. “It’s nice to have a man who cares about his skin and cares about his appearance, buys products and asks me about them. ‘Hey, what about this? What about this?'”

The MUA star then delved into the practices and routines that keep her glowing, which include monthly facials (“This is not a game”) and a really, very clean food regimen.

“Of course, we start with a foaming cleanser because I do his stage makeup so that his hairline and certain things stay intact because he sweats a lot,” she says. “If you haven’t seen Usher perform, it’s like a waterfall. So I placed on some makeup that principally won’t come off together with his sweat. Moisturizing foaming cleansing oil It’s amazing since it breaks down product, it breaks down dirt, it breaks down oils, in order that’s definitely where we start.”

Next up is a brand new vitamin C eye cream. Okanlawon received the product ahead of its September launch and has been using it often on the star’s eyes for several months. She says it’s a must have in any skincare routine.

“Usher is a very good, handsome man. But he’s still 45, so eye cream is very important, and eye cream with vitamin C is amazing,” she says. “It’s preventative, so don’t wait until a certain age. Start using eye cream.”

Then they use Vitamin C Serum and finish your pre-makeup workout by moisturizing your body with Cerave Daily Moisturizing Balmwhich apply together.

“We use serum because serum is very important. Vitamin C helps brighten the skin,” she says. “His skin is very elastic because he takes good care of it. It’s easy, he’s easy.”

What Usher does night after night in front of packed audiences is not easy, but with guidance from Okanlawon and Cerave’s Skin Renewing line of beauty products, she all the time looks gorgeous when she does it.


This article was originally published on : www.essence.com
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Health and Wellness

The Way We Think About “Obesity” and Body Weight Is Changing, Here’s Why

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From doctor’s offices to family gatherings, larger people report being bombarded unsolicited advice about their eating and exercise habits. The underlying message? “They just need to lose weight” to solve almost any health problem.

Society’s give attention to weight has shaped the best way most Australians view health and body weight, which frequently pushes them towards unhealthy thoughts and behaviors in pursuit of the “perfect” figure.

However, the best way society views obesity and body weight is changing, and these changes are being confirmed by science.


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Policymakers and health researchers are increasingly recognizing the harmful effects stigmatizing language and attitude towards individuals with a bigger physique.

Let’s have a look at how attitudes towards obesity have modified through the years and what this implies for public health and healthcare in Australia.

From Personal Responsibility to Complex Chronic Illness

Until recently, weight control was it will likely be considered a private responsibilityObesity was believed to be the results of poor eating regimen and lack of physical activity, coupled with personal and moral failure.

This narrative was reflected in public health policy, which used phrases similar to “he was obese“and the “epidemic of o*c*lness”. It has been shown that such language reinforce negative stereotypes people with larger builds as “lazy” and lacking willpower.

These stereotypes result in stigmatization and weight discrimination, which is still common today. Health professionals similar to dietitians report that Weight stigma (from other people and internally) is a standard and ongoing challenge that ladies need to cope with throughout their careers.

The narrative around personal responsibility has modified lately because it begins to think about broader determinants of health. Research has identified a spread of psychological, social, biological and systemic aspects contribute to rising rates of obesity, similar to socioeconomic status, genetics, medications and environment.

As a result, public health experts consider that is not any longer appropriate use language that refers to obesity as a “lifestyle” issue.

Until recently, weight management was seen as a private responsibility.
World Obesity Federation

Professionals throughout medicine, psychology and dietetics additionally they responded by updating their language standards to prioritize person-first language (for instance, “person living with o*b*lihood”), recognizing a shift away from viewing o*b*lihood as a private failure.

In 2014, the American Medical Association of the United States classified obesity as a chronic diseasecontrary to the recommendations of the Science and Public Health Committee. The decision has sparked widespread dissatisfaction and debate, with claims that it causes unnecessary discrimination and pathologizes normal changes within the human body over time.

The debate continues here in Australiabut no classification has yet been made.

Weight-focused and weight-sensitive narratives

Recent policy documents in Australia similar to National Anti-Obesity Strategy 2022–2032acknowledge the broader perspective of o*b*st. But the policy and practice in Australia remain mainly focused on weight. They encourage weight reduction as a health goal and recommend deliberately avoiding weight gain.

Weight-Focused Approaches to Health They were criticized for the dearth of long-term (longer than five years) evidence of their effectiveness and for causing unintended effects.

Rather than promoting health, weight-focused approaches could cause harm, similar to increased weight stigma and weight cycling (repeated weight reduction and regain). Both weight mark AND weight cycles are related to negative long-term effects on physical and mental health.

Weight-sensitive approaches to health are gaining popularity instead approach that supports people to eat healthily and exercise repeatedly, no matter their desire to shed weight. This approach goals to enhance access to health care and has been shown to enhance overall physical and mental health.

Approaches similar to Health at every size and intuitive eating are key examples of promoting health and wellness without specializing in weight.

Weight-sensitive approaches have he was met with criticismHowever, there are concerns that these approaches will not be supported by empirical evidence and might not be suitable for people needing support with weight management.

What does this mean for us?

While our views on obesity are always changing, it is crucial to hearken to plus-size people and ensure they’ve equal, protected and satisfactory access to healthcare.

Advocates like Size Inclusive Health Australia recommending actions to cut back weight-related stigma and discrimination in order that health is inclusive of all body shapes and sizes.

There are guidelines and recommendations on counter weight stigma and adopt a weight-sensitive approach to health, similar to: Size-sensitive health promotion guidelines and Eating Disorder Safety Guidelines.

Policy, research and practice should proceed to synthesise and understand the evidence surrounding weight-sensitive approaches, in keeping with changing narratives around weight and health. This will support the design, implementation and evaluation of weight-sensitive initiatives in Australia.

This article was originally published on : theconversation.com
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