Technology
We’re about to learn a lot more about how the human body responds to space
We could also be entering a renaissance in human spaceflight research as record numbers of personal residents enterprise into space and scientists improve techniques for collecting data on these intrepid test subjects.
An indication that a renaissance is at hand got here earlier this week when a paper appeared in the journal Nature collection of papers detailing the physical and mental changes the four-person Inspiration4 crew experienced almost three years ago. This mission, in cooperation with SpaceX, launched on September 15, 2021 and returned to Earth three days later.
During the mission, the crew experienced a broad set of moderate molecular changes, immune system dysregulation, and mild declines in cognitive performance. But researchers are only able to analyze the data – more than 100,000 health-related data points – because the four-person crew was able to reliably collect it.
This is a larger achievement than you would possibly think. The Inspiration4 crew underwent extensive training, largely thanks to SpaceX, which provided them with a Dragon capsule for the flight to orbit. However, their preparation still differs from that of NASA astronauts aboard the ISS, who also repeatedly perform a variety of health tests on themselves. This includes ultrasounds, cognitive tests, biopsies, blood and saliva tests, skin swabs and sensorimotor tests.
“You can conduct research in space with private participation and that is the number one (research) result,” Dr. Dorit Donoviel said in a recent interview. Dr. Donoviel is a co-author of a paper published in the journal Nature and an associate professor at the Center for Space Medicine at Baylor University. He can be executive director of the NASA-funded Translational Research Institute for Space Health (TRISH), which conducts and funds cutting-edge research to improve human safety in space.
“I’ll be honest, no one was sure whether we would be able to collect a reasonable amount of data, whether we would be able to implement it, whether ordinary people who had never had any contact with scientific research would be able to do something that we would actually be able to analyze” – she continued, referring to the Inspiration4 mission.
In some obvious ways, the Inspiration4 crew is anything but strange: the mission’s leader, Jared Isaacman, is a billionaire who began a payment processing company at age 16; Hayley Arcenaux is a physician assistant at the world-renowned St. George’s Children’s Research Hospital. Jude; Sian Proctor is a PhD pilot and lecturer in geology at university level; and Christopher Sembroski is a former United States Air Force journeyman whose long profession as an aerospace engineer led him to his current workplace, Blue Origin.
Yet they got here to Inspiration4 as novices in spaceflight. This meant that TRISH researchers had to develop a test battery that could possibly be performed with minimal training. The Inspiration4 crew also wore Apple watches, and the capsule was equipped with environmental sensors that researchers were able to link to the results of other tests. The correlation of the data is “remarkable,” Dr. Donoviel said, but it surely gave researchers unique insight into how changes in a closed environment affect parameters similar to heart rate and cognitive performance.
Overall, researchers try to move toward digitizing tests and increasing passive data collection to reduce the cognitive load on the private astronaut. (NASA astronauts also take cognitive tests, but they do it with pencil and paper, Dr. Donoviel said.)
Collecting such information might be crucial as the number of personal residents venturing into space increases, which is able to almost actually occur in the coming decade. Scientists will have the option to higher understand the impact of spaceflight on individuals who don’t fit the mold of the typical NASA astronaut: male, white, and other people in the highest percentiles of physical and cognitive ability. However, this may only be possible if future space tourists want to collect data.
More data means a higher understanding of how spaceflight affects women compared to men, or it could help future space tourists with pre-existing conditions understand how they may fare in a zero-gravity environment. The results of the Inspiration4 project are promising, especially for space tourism: the TRISH paper concluded that, based on data from this mission, short-duration missions don’t pose significant health risks. This latest preliminary discovery adds to existing data that shows longer stays in space – on this case 340 days – is probably not as dangerous as once thought.
So far, business providers, from Axiom Space to SpaceX to Blue Origin, have been more than willing to work with TRISH and have agreed to standardize and mix data collected on their missions, Dr. Donoviel said.
“Everyone is competing for these people (as customers), but this allows them to contribute to a common knowledge base,” she added.
This is just the starting. The increase in the variety of non-governmental spaceflight missions raises major questions related to the standards, ethics and regulations of research involving humans in space. While more private residents are likely to go to space than ever before, will they be inquisitive about being guinea pigs for further scientific research? Would a private astronaut paying $50 million for luxury space tourism want to spend his time in orbit having ultrasounds performed on himself or having his temporary cognitive decline meticulously measured?
Probably; probably not. Last 12 months, Donoviel co-authored a publication entitled article in Science calling, amongst other things, for the development of a algorithm to govern business spaceflight missions. One of the principles the authors called for is social responsibility – essentially the idea that non-public astronauts likely have increased social responsibility for advancing research.
“If you go into space, you will rest on the laurels of all the public funds that made it possible for you to go to space. Taxpayers paid for all these space capabilities that have now made space travel possible. So you owe taxpayers research,” Dr. Donoviel argued. She added that advances in wearable technology have only eased the burden on study participants – not only with the Apple Watch, but in addition with technologies like Biobutton device that repeatedly accumulates multiple vital signs or a sweat stain.
“We won’t make your life difficult, we won’t stab you with a needle, we won’t force you to do an ultrasound, but put on the Biobutton and a sweatband.”
Technology
The company is currently developing washing machines for humans
Forget about cold baths. Washing machines for people may soon be a brand new solution.
According to at least one Japanese the oldest newspapersOsaka-based shower head maker Science has developed a cockpit-shaped device that fills with water when a bather sits on a seat in the center and measures an individual’s heart rate and other biological data using sensors to make sure the temperature is good. “It also projects images onto the inside of the transparent cover to make the person feel refreshed,” the power says.
The device, dubbed “Mirai Ningen Sentakuki” (the human washing machine of the longer term), may never go on sale. Indeed, for now the company’s plans are limited to the Osaka trade fair in April, where as much as eight people will have the option to experience a 15-minute “wash and dry” every day after first booking.
Apparently a version for home use is within the works.
Technology
Zepto raises another $350 million amid retail upheaval in India
Zepto has secured $350 million in latest financing, its third round of financing in six months, because the Indian high-speed trading startup strengthens its position against competitors ahead of a planned public offering next yr.
Indian family offices, high-net-worth individuals and asset manager Motilal Oswal invested in the round, maintaining Zepto’s $5 billion valuation. Motilal co-founder Raamdeo Agrawal, family offices Mankind Pharma, RP-Sanjiv Goenka, Cello, Haldiram’s, Sekhsaria and Kalyan, in addition to stars Amitabh Bachchan and Sachin Tendulkar are amongst those backing the brand new enterprise, which is India’s largest fully national primary round.
The funding push comes as Zepto rushes so as to add Indian investors to its capitalization table, with foreign ownership now exceeding two-thirds. TechCrunch first reported on the brand new round’s deliberations last month. The Mumbai-based startup has raised over $1.35 billion since June.
Fast commerce sales – delivering groceries and other items to customers’ doors in 10 minutes – will exceed $6 billion this yr in India. Morgan Stanley predicts that this market shall be value $42 billion by 2030, accounting for 18.4% of total e-commerce and a pair of.5% of retail sales. These strong growth prospects have forced established players including Flipkart, Myntra and Nykaa to cut back delivery times as they lose touch with specialized delivery apps.
While high-speed commerce has not taken off in many of the world, the model seems to work particularly well in India, where unorganized retail stores are ever-present.
High-speed trading platforms are creating “parallel trading for consumers seeking convenience” in India, Morgan Stanley wrote in a note this month.
Zepto and its rivals – Zomato-owned Blinkit, Swiggy-owned Instamart and Tata-owned BigBasket – currently operate on lower margins than traditional retail, and Morgan Stanley expects market leaders to realize contribution margins of 7-8% and adjusted EBITDA margins to greater than 5% by 2030. (Zepto currently spends about 35 million dollars monthly).
An investor presentation reviewed by TechCrunch shows that Zepto, which handles greater than 7 million total orders every day in greater than 17 cities, is heading in the right direction to realize annual sales of $2 billion. It anticipates 150% growth over the following 12 months, CEO Aadit Palicha told investors in August. The startup plans to go public in India next yr.
However, the rapid growth of high-speed trading has had a devastating impact on the mom-and-pop stores that dot hundreds of Indian cities, towns and villages.
According to the All India Federation of Consumer Products Distributors, about 200,000 local stores closed last yr, with 90,000 in major cities where high-speed trading is more prevalent.
The federation has warned that without regulatory intervention, more local shops shall be vulnerable to closure as fast trading platforms prioritize growth over sustainable practices.
Zepto said it has created job opportunities for tons of of hundreds of gig employees. “From day one, our vision has been to play a small role in nation building, create millions of jobs and offer better services to Indian consumers,” Palicha said in an announcement.
Regulatory challenges arise. Unless an e-commerce company is a majority shareholder of an Indian company or person, current regulations prevent it from operating on a listing model. Fast trading corporations don’t currently follow these rules.
Technology
Wiz acquires Dazz for $450 million to expand cybersecurity platform
Wizardone of the talked about names within the cybersecurity world, is making a major acquisition to expand its reach of cloud security products, especially amongst developers. This is buying Dazzlespecialist in solving security problems and risk management. Sources say the deal is valued at $450 million, which incorporates money and stock.
This is a leap within the startup’s latest round of funding. In July, we reported that Dazz had raised $50 million at a post-money valuation of just below $400 million.
Remediation and posture management – two areas of focus for Dazz – are key services within the cybersecurity market that Wiz hasn’t sorted in addition to it wanted.
“Dazz is a leader in this market, with the best talent and the best customers, which fits perfectly into the company culture,” Assaf Rappaport, CEO of Wiz, said in an interview.
Remediation, which refers to helping you understand and resolve vulnerabilities, shapes how an enterprise actually handles the various vulnerability alerts it could receive from the network. Posture management is a more preventive product: it allows a company to higher understand the scale, shape and performance of its network from a perspective, allowing it to construct higher security services around it.
Dazz will proceed to operate as a separate entity while it’s integrated into the larger Wiz stack. Wiz has made a reputation for itself as a “one-stop shop,” and Rappaport said the integrated offering will proceed to be a core a part of it.
He believes this contrasts with what number of other SaaS corporations are built. In the safety industry, there are, Rappaport said, “a lot of Frankenstein mashups where companies prioritize revenue over building a single technology stack that actually works as a platform.” It could be assumed that integration is much more necessary in cybersecurity than in other areas of enterprise IT.
Wiz and Dazz already had an in depth relationship before this deal. Merat Bahat — the CEO who co-founded Dazz with Tomer Schwartz and Yuval Ofir (CTO and VP of R&D, respectively) — worked closely with Assaf Rappaport at Microsoft, which acquired his previous startup Adallom.
After Rappaport left to found Wiz together with his former Adallom co-founders, CTO Ami Luttwak, VP of Product Yinon Costica and VP of R&D Roy Reznik, Bahat was one in all the primary investors. Similarly, when Bahat founded Dazz, Assaf was a small investor in it.
The connection goes deeper than work colleagues. Bahat and Rappaport are also close friends, and she or he was the second family of Mickey, Rappaport’s beloved dog, referred to as Chief Dog Officer Wiz (together with LinkedIn profile). Once the deal was done, the 2 faced two very sad events: each Bahat and Mika’s mother died.
“We hope for a new chapter of positivity,” Bahat said. The cycle of life does indeed proceed.
Rumors of this takeover began to appear earlier this month; Rappaport confirmed that they then began talking seriously.
But that is not the one M&A conversation Wiz has gotten involved in. Earlier this 12 months, Google tried to buy Wiz itself for $23 billion to construct a major cybersecurity business. Wiz walked away from the deal, which might have been the biggest in Google’s history, partly because Rappaport believed Wiz could turn into a fair larger company by itself terms. And that is what this agreement goals to do.
This acquisition is a test for Wiz, which earlier this 12 months filled its coffers with $1 billion solely for M&A purposes (it has raised almost $2 billion in total, and we hear the subsequent round will close in just a few weeks). . Other offers included purchasing Gem security for $350 million, but Dazz is its largest acquisition ever.
More mergers and acquisitions could also be coming. “We believe next year will be an acquisition year for us,” Rappaport said.
In an interview with TC, Luttwak said that one in all Wiz’s priorities now’s to create more tools for developers that have in mind what they need to do their jobs.
Enterprises have made significant investments in cloud services to speed up operations and make their IT more agile, but this shift has include a significantly modified security profile for these organizations: network and data architectures are more complex and attack surfaces are larger, creating opportunities for malicious hackers to find ways to to hack into these systems. Artificial intelligence makes all of this far more difficult when it comes to malicious attackers. (It’s also a chance: the brand new generation of tools for our defense relies on artificial intelligence.)
Wiz’s unique selling point is its all-in-one approach. Drawing data from AWS, Azure, Google Cloud and other cloud environments, Wiz scans applications, data and network processes for security risk aspects and provides its users with a series of detailed views to understand where these threats occur, offering over a dozen products covering the areas, corresponding to code security, container environment security, and provide chain security, in addition to quite a few partner integrations for those working with other vendors (or to enable features that Wiz doesn’t offer directly).
Indeed, Wiz offered some extent of repair to help prioritize and fix problems, but as Luttwak said, the Dazz product is solely higher.
“We now have a platform that actually provides a 360-degree view of risk across infrastructure and applications,” he said. “Dazz is a leader in attack surface management, the ability to collect vulnerability signals from the application layer across the entire stack and build the most incredible context that allows you to trace the situation back to engineers to help with remediation.”
For Dazz’s part, once I interviewed Bahat in July 2024, when Dazz raised $50 million at a $350 million valuation, she extolled the virtues of constructing strong solutions and this week said the third quarter was “amazing.”
“But market dynamics are what trigger these types of transactions,” she said. She confirmed that Dazz had also received takeover offers from other corporations. “If you think about the customers and joint customers that we have with Wiz, it makes sense for them to have it on one platform.”
And a few of Dazz’s competitors are still going it alone: Cyera, like Dazz, an authority in attack surface management, just yesterday announced a rise of $300 million at a valuation of $5 billion (which confirms our information). But what’s going to he do with this money? Make acquisitions, after all.
Wiz says it currently has annual recurring revenue of $500 million (it has a goal of $1 billion ARR next 12 months) and has greater than 45% of its Fortune 100 customers. Dazz said ARR is within the tens of hundreds of thousands of dollars and currently growing 500% on a customer base of roughly 100 organizations.
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