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Why do I have to take some medications with meals?

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Have you ever been told to take your medication with food and wondered why? Maybe you wondered in case you really needed to?

There are various reasons, and sometimes complex scientific and chemical bases, why it could be beneficial to take medications with food.

To complicate matters, some similar medications must be taken otherwise. For example, the antibiotic amoxicillin with clavulanic acid (sold as Amoxil Duo Forte) is beneficial to be taken with food, while amoxicillin alone (sold as Amoxil) will be taken with or without food.

Different brands of the identical medication might also have different recommendations for taking it with food.

Food affects the absorption of medicine

Food can affect how quickly and the way much of a drug is absorbed into the body over time. 40% of medicines taken orally.

When you have food in your stomach, the composition of your digestive juices changes. This includes things like fluid volume, density, pH (which becomes less acidic with food), surface tension, movement, and the quantity of salts within the bile. These changes can impair or enhance the absorption of the drug.

Eating a meal also delays the speed at which the contents of the stomach move into the small intestine – that is often known as stomach emptyingThe small intestine has a big surface area and a wealthy blood supply – and that is the foremost site of drug absorption.

Eating food with this medication will delay its effects.
Farhad/Pexels

Eating a bigger meal or one with lots of fiber delays stomach emptying greater than a smaller meal. Sometimes health experts recommend taking a medicine with food to help the body absorb the medication more slowly.

However, if the medication will be taken with or without food – like paracetamol – and you would like it to work faster, take it on an empty stomach.

Food could make medications higher tolerated

Have you ever taken a drugs on an empty stomach and felt nauseous shortly after? Some medicines may cause stomach upset.

For example, metformin is a drug that lowers blood glucose levels and treats type 2 diabetes and polycystic ovary syndrome. It often causes gastrointestinal symptoms, with one in 4 users affectedTo combat these unwanted side effects, it is strongly recommended to take the medication with a meal.

The same advice is given with corticosteroids (akin to prednisolone/prednisone) and some antibiotics (akin to doxycycline).

Taking some medications with food makes them higher tolerated and increases the possibility of taking them for the prescribed time period.

Can food make medicines safer?

Ibuprofen is one of the crucial commonly used over-the-counter medications, with one in five Australians admitting to using it inside two weeks.

Although ibuprofen is effective in treating pain and inflammation, it could affect the stomach by inhibiting protective prostaglandins, increasing the chance bleeding, ulceration and perforation with long-term use.

But there there will not be enough research to show that taking ibuprofen with food reduces this risk.

Long-term use might also affect kidney function, especially in people with comorbidities or dehydration.

This Australian Drug Manualwhich provides guidance to doctors on the use and dosage of medications, recommends taking ibuprofen (sold as Nurofen and Advil) with a glass of water – or with a meal if it causes stomach upset.

A pharmacist dispenses medication to a customer
If it doesn’t upset your stomach, you’ll be able to take ibuprofen with water.
Tbel Abuseridze/Unsplash

Systematic review published in 2015. Food has been found to delay ibuprofen’s transport to the small intestine and absorption, which delays the therapeutic effect and time to pain relief. Taking short courses of ibuprofen without food has also been found to reduce the necessity for added doses.

To reduce the chance of ibuprofen damaging your stomach or kidneys, use the bottom effective dose for the shortest time possible, stay hydrated, and avoid taking other medications. non-steroidal anti-inflammatory drugs at the identical time.

For individuals who have been taking ibuprofen for a very long time and are at greater risk of developing unwanted side effects within the digestive tract (e.g. people with a history of ulcers or the elderly), your doctor may start your treatment with proton pump inhibitora drug that reduces the secretion of gastric acid and protects the gastric mucosa.

How much food do you wish?

When it’s mandatory to take medication with a meal, what dose is sufficient?

Sometimes with medications like prednisone/prednisolone, a full glass of milk or a couple of crackers will suffice.

However, most head-to-head studies that compare the consequences of a drug “with food” and “without” typically use a heavy meal to define “with food.” So a cracker is probably not enough, especially for people with sensitive stomachs. A more substantial meal that features a mixture of fat, protein, and carbohydrates is usually beneficial.

Your doctor can advise you on which medications must be taken with meals and the way they affect the digestive system.

This article was originally published on : theconversation.com
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Health and Wellness

‘Preventable’ death of black mother after complications first linked to abortion ban

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Amber Thurman, Roe v. Wade, theGrio.com

A Black mother died in Georgia after a strict state law banning abortion caused an almost 24-hour delay in her care.

In August 2022, 28-year-old Amber Nicole Thurman went to a North Carolina clinic to have an abortion, People Magazine reportedShe couldn’t get the procedure in Georgia, where she lived, because she was six weeks pregnant — and after Roe v. Wade was overturned in 2022, the state banned abortions after six weeks of pregnancy.

The clinic gave her the pregnancy-terminating pills, mifepristone and misoprostol, which she took home to Georgia. A number of days later, Thurman developed a rare complication during which she didn’t expel all of the fetal tissue, according to ProPublicathe editorial office that first reported on her case.

Thurman, a medical assistant and mother of a 6-year-old boy, began experiencing heavy bleeding and pain before she eventually collapsed at home. Her boyfriend called an ambulance and she or he was taken to Piedmont Henry Hospital in Stockbridge. The remaining tissue caused her to develop a highly dangerous infection often called sepsis.

However, due to Georgia’s anti-abortion laws, doctors didn’t perform a D&C (dilation and curettage). Despite losing consciousness within the hospital room and rapidly deteriorating, she didn’t receive treatment for nearly 24 hours.

ProPublica reports that an official state commission found that doctors waited 20 hours before the surgery while monitoring Thurman’s infection status — during which era her blood pressure dropped to dangerous levels and her organs shut down.

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After her death, a state investigation concluded it was “preventable” — and ProPublica said Thurman’s case is the first known “preventable” case involving an abortion.

The publication notes that it should likely take one other two years to fully understand the impact of Roe v. Wade’s defeat, as many hospitals have a two-year delay in reporting the cause of patient deaths. But it’s not surprising that the first public story is a few black woman. The maternal health crisis continues to disproportionately affect black moms.

What happened to Thurman isn’t only one of the risks of abortion. It may occur in cases of miscarriage, vaginal delivery or cesarean section, according to Mayo ClinicWhen many warned that overturning Roe v. Wade and letting states resolve could have negative impacts on women’s health overall, this is strictly what many feared.

“We actually have proven evidence of something we already knew — that abortion bans kill people,” said Mini Timmaraju, president of the abortion rights group Reproductive Freedom for All. Mother Jones on Thurman’s case. “This can’t go on.”

Meanwhile in Georgia, Dr. Krystal “KR” RedmanSPARK co-founder, told the outlet: “Amber’s case is just one example of the ongoing systemic neglect that continues to claim the lives of Black people.”

Redman added: “Reproductive justice is not just about access to abortion, but also about the broader right to high-quality, comprehensive, full-spectrum, culturally modest, life-saving health care for all of us.”

This article was originally published on : thegrio.com
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Quincy shares positive updates about his relationship with his father, Al B. Sure!

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Artist Quincy Brown, the adopted son of Sean “Diddy” Combs, sat down with Angela Yee on her podcast to debate his relationship with his biological father, Al B. Sure! It’s a timely conversation considering Quincy’s father, Diddy, was recently arrested by federal agents in New York. for conspiracy to commit racketeering, sex trafficking by use of force, fraud or coercion, and transportation for the aim of prostitution.

Asked about the status of his relationship with Al B. Sure! following an open letter he wrote to him in 2009, Quincy said they were currently “fine,” adding that he had spoken to him just days earlier when B. Sure!, 56, congratulated him on his latest album ETA.

“It’s a cool relationship,” he said. “He tries to act like a father a lot, but that’s not really where we are in life. We’re buddies, more than anything else,” Brown, 33, added.

Quincy also stated that the character of their relationship is to spend time and do things together. Speaking of which, they were last seen together on the Black Excellence Brunch held on the White House, in order that they did indeed spend a while together.

“I feel like that’s what we’re all about, the awareness that we’re two grown men. We can talk about anything and everything,” he concluded.

If you remember, in 2009, Quincy wrote an open letter to his biological father by which he criticized him for his long-term absence from home.

“Albert Brown, aka ‘Al B Sure!’ is my biological father, but Sean Combs, aka ‘Diddy,’ has been a fatherly figure in my life for as long as I can remember. Sean Combs is someone I respect and appreciate as a father figure,” he said in a lengthy open letter on the time.

With Diddy’s dark past quickly emerging, in March 2024, B. Sure! took to social media to put in writing a brief open letter to his son, reminding him that the door to his house is wide open.

“#LetterToMySon! Come home. [door] is wide open. You’re safe here, son! I love you, Popz, Your Biological,” he wrote within the caption.

Brown was born in 1991 to the late Kim Porter and Al B. Sure! In 2020, the singer revealed that they were also briefly married, surprising many fans. Porter began dating Combs when Quincy was around three years old and eventually adopted him.

We’re glad Quincy has a father he can count on while Diddy stays in custody awaiting trial.

This article was originally published on : www.essence.com
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SEE | The Usefulness of Having a Community in the Fashion Industry – Essence

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This article was originally published on : www.essence.com
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