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Considering Taking Wegova to Lose Weight? Here Are the Risks and Benefits – and How It Differs from Ozempic

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Slimming medicine Vegi is now available in Australia.

Wegovy is run as a once-weekly injection and is approved specifically for weight management. It is meant to be used together with a reduced energy food plan and increased physical activity.

So how does Wegovy work, and how much weight are you able to expect to lose while taking it? And what are the potential risks—and costs—for individuals who use it?

Let’s have a look at what science says.

What is Wegovy?

Wegovy is the brand name for the drug semaglutide. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1RA). This means it makes your body’s own hormone glucagon-like peptide-1, or GLP-1 for brief, work higher.

Normally, if you eat, your body releases the hormone GLP-1, which helps signal your brain that you just’re full. Semaglutides enhance this effect, leading to feelings of fullness even if you haven’t eaten anything.

Another role of GLP-1 is to stimulate the body to produce more insulin, a hormone that helps lower blood glucose (sugar) levels. That is why semaglutides are utilized in just a few years in the treatment of type 2 diabetes.

Wegovy is self-administered to the patient once per week.
S. Becker/Shutterstock

How is Wegovy different from Ozempic?

Like Wegovy, Ozempic is a semaglutide. The way Wegovy and Ozempic work in the body is actually the same. They are manufactured by the same pharmaceutical company, Novo Nordisk.

There are, nevertheless, two differences:

1) They are approved for 2 different (but related) reasons.

In Australia (and the United States) Ozempic is approved to be used to improve blood glucose levels in adults with type 2 diabetes. By effectively managing blood glucose levels, the medicine goals to reduce the risk of great complications comparable to heart disease.

Wegovy is approved to be used together with food plan and exercise for individuals who have a body mass index (BMI) of 30 or more, or 27 or more but produce other health conditions comparable to hypertension.

Wegovy can be utilized in people aged 12 and older. Like Ozempic, Wegovy is designed to reduce the risk of future health complications, including heart disease.

2) Both are injectable but are available in different concentrations.

Ozempic is on the market in disposable pens with pre-filled doses of 0.25 mg, 0.5 mg, 1 mg, or 2 mg per injection. The dose could be slowly increased to a maximum of two mg per week if needed.

Wegovy is on the market in pre-filled disposable pens with doses of 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, or 2.4 mg. Treatment is initiated at a dose of 0.25 mg once per week for 4 weeks, after which the dose is steadily increased to a maintenance dose of two.4 mg per week.

While it’s unknown what impact the introduction of Wegovy can have on the availability of Ozempic, Ozempic continues to be available It is predicted that there might be few of them until the end of 2024.

Is Wegovy effective for weight reduction?

Considering that Wegovy is a semaglutide, there’s very strong evidence can assist people reduce weight and keep it off.

Recent test found that over 4 years, participants taking Wevovy as directed experienced a mean weight reduction of 10.2% of their body weight and a discount in waist circumference of seven.7 cm.

Analyses showed that individuals who stopped taking the drug lost about two-thirds of their weight. recovered.

A man leans on the railing of a bridge
Wegovy can assist people reduce weight and keep it off – while taking the medication.
Mladen Mitrinovic/Shutterstock

What are the unwanted side effects of Wegova?

Most common unwanted side effects there’s nausea and vomiting.

However, other serious unwanted side effects are also possible due to the drug’s effects on the entire body. Thyroid tumors and cancer have been identified as risks in animal studies, but are rare in humans. scientific literature.

In the four-year-old Wegovy test16.6% of participants who received Wegovy (1,461 people) experienced an adversarial event that led to everlasting discontinuation of the drug. This was higher than 8.2% of participants (718 people) who received placebo (no energetic ingredient).

Side effects included gastrointestinal upset (including nausea and vomiting), which occurred in 10% of individuals taking Wegovy compared with 2% of individuals taking placebo.

Gallbladder dysfunction occurred in 2.8% of individuals taking Wegovy and 2.3% of individuals taking placebo.

Recently, there have been concerns about suicidal thoughts and behaviors, global evaluation greater than 36 million adversarial event reports related to the use of semaglutide (Ozempic or Wegovy) since 2000 were reviewed.

There were 107 reports of suicidal thoughts and self-harm amongst people taking semaglutide, including, unfortunately, six actual deaths. When people stopped taking the drug, 62.5% said the thoughts stopped. We do not know if the dose, weight reduction, previous mental health conditions or use of antidepressants played a job.

There are also growing concerns about the negative impact of semaglutide on our social and emotional relationships with food. Thematic AND scientific evidence suggests that individuals taking semaglutide significantly reduce their every day food intake (as expected), skipping meals and avoiding social gatherings – which isn’t very nice for people and their family members.

How can I access Wegovy?

Wegovy could be purchased at a pharmacy with a prescription from a health care provider.

But there’s a high price. Wegovy is currently not subsidized through the Pharmaceutical Benefits Scheme, leaving patients to bear the cost. The current cost is estimated at around 460 Australian dollars monthly dose.

If you’re considering Wegovy, arrange Consult your doctor for individual advice.

This article was originally published on : theconversation.com
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Health and Wellness

US communities phase out fluoride use in public drinking water

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fluoride, water


There is a battle raging in American cities over whether to proceed using fluoride in water.

This is a process generally known as fluoridation that began around 1945. According to to the American Cancer Society became popular across the country after scientists noticed that individuals living in water with higher concentrations of fluoride had less tooth decay.

In 1962, the U.S. Public Health Service (PHS) advisable adding fluoride to public drinking water supplies to forestall tooth decay. The American Cancer Society estimates that fluoride is currently used in public drinking water supplied to roughly three in 4 Americans.

However, opponents have been warning for years that fluoride in drinking water is unsafe to devour. One of the organizations leading this initiative is Fluoride Action Network (FAN). The organization, whose mission is to lift awareness of what it claims is the “toxicity of fluoride compounds,” says many of the world’s developed countries don’t use fluoride in drinking water at the identical levels as America, or in any respect.

The organization says yes it helped over 500 communities successfully reject fluoridation, and there could also be more.

Federal leaders have gotten increasingly vocal in their support for ending the use of fluoride

While FAN says communities have rejected fluoridation for the past few a long time and the method has stalled in consequence, the fight has been thrust into the highlight over the past few months.

First, the National Toxicology Program, a federal agency throughout the Department of Health and Human Services, reported with “moderate certainty” that there may be an association between communities with higher levels of fluoride exposure and lower IQ in children. According to the Associated Press, these communities use greater than twice the advisable limit.

A month later, a federal judge apparently ordered the U.S. Environmental Protection Agency (EPA) to further regulate fluoride in drinking water because higher levels could affect children.

Robert F. Kennedy, nominated by President-elect Donald Trump to direct the Department of Health and Human Services, announced an end to fluoridation.


This article was originally published on : www.blackenterprise.com
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Health and Wellness

WATCH: Cynthia Erivo on the importance of being a sister – Essence

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This article was originally published on : www.essence.com
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Phenergan is no longer recommended for children under 6 years of age due to the risk of hallucinations. Here’s what you can use instead

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The Australian Drugs Regulatory Authority has issued an order safety warning over Phenergan and related products containing the antihistamine promethazine.

The Therapeutic Goods Administration has stated that over-the-counter products shouldn’t be given to children under six years of age due to concerns about serious unwanted side effects akin to hyperactivity, aggression and hallucinations. Breathing may turn into slow or shallow, which can be fatal.

When high doses are administered to young children, difficulties in learning and understanding, including reversible cognitive deficit and mental disability, may occur. – said the TGA.

The latest warning follows international and Australian concerns about the drug in young children, which is commonly used to treat conditions akin to hay fever and allergies, motion sickness and for short-term sedative effects.

What is promethazine?

Promethazine is a “first generation” antihistamine that has been sold over the counter in Australian pharmacies for a long time for a spread of conditions.

Unlike many other drugs, first-generation antihistamines can cross the blood-brain barrier. This means they affect your brain chemistry, making you feel drowsy and sedated.

In adults, this will likely be useful for sleep. However, in children, these drugs can cause serious unwanted side effects on the nervous system, including those mentioned on this week’s safety alert.

We’ve known about this for a while

We have known about the serious unwanted side effects of promethazine in young children for a while.

Advice regarding 20 years ago In the United States, the drug was not recommended for use in children under two years of age. In 2022, an Australian Medicines Advisory Committee made its own suggestion to increase the age to six. New Zealand released similar warnings and advice in May this 12 months.

Over the last ten years, there have been 235 cases of serious unwanted side effects from promethazine in each children and adults reported to the TGA. Of the 77 deaths reported, one was a toddler under six years of age.

Reported unwanted side effects in each adults and children included:

  • 13 cases of accidental overdose (leading to 11 deaths)
  • eight cases of hallucinations
  • seven cases of slow or shallow respiration (leading to 4 deaths)
  • six cases of decreased consciousness (leading to five deaths).

TGA security alert comes after an internal investigation by the manufacturer of Phenergan, Sanofi-Aventis Healthcare. This investigation was initiated in 2022 advice from the Medicines Advisory Committee. The company has now updated its information for consumers and healthcare professionals.

What can you use instead?

If you have allergies or hay fever in young children, non-sedating antihistamines akin to Claratine (loratadine) or Zyrtec (cetirizine) are preferred. They provide relief without the risk of sedation and other disturbing unwanted side effects of promethazine.

If symptoms of a chilly or cough occur, parents must be reassured that these symptoms will normally subside with time, fluid intake, and rest.

Saline nasal sprays, adequate hydration, a humidifier or elevating the child’s head can relieve the congestion related to hay fever. Oral products containing phenylephrine marketed for nasal congestion must be avoided because evidence shows that this is the case This article was originally published on : theconversation.com

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