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Considering Taking Wegova to Lose Weight? Here Are the Risks and Benefits – and How It Differs from Ozempic

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Slimming medicine Vegi is now available in Australia.

Wegovy is run as a once-weekly injection and is approved specifically for weight management. It is meant to be used together with a reduced energy food plan and increased physical activity.

So how does Wegovy work, and how much weight are you able to expect to lose while taking it? And what are the potential risks—and costs—for individuals who use it?

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Let’s have a look at what science says.

What is Wegovy?

Wegovy is the brand name for the drug semaglutide. Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1RA). This means it makes your body’s own hormone glucagon-like peptide-1, or GLP-1 for brief, work higher.

Normally, if you eat, your body releases the hormone GLP-1, which helps signal your brain that you just’re full. Semaglutides enhance this effect, leading to feelings of fullness even if you haven’t eaten anything.

Another role of GLP-1 is to stimulate the body to produce more insulin, a hormone that helps lower blood glucose (sugar) levels. That is why semaglutides are utilized in just a few years in the treatment of type 2 diabetes.

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Wegovy is self-administered to the patient once per week.
S. Becker/Shutterstock

How is Wegovy different from Ozempic?

Like Wegovy, Ozempic is a semaglutide. The way Wegovy and Ozempic work in the body is actually the same. They are manufactured by the same pharmaceutical company, Novo Nordisk.

There are, nevertheless, two differences:

1) They are approved for 2 different (but related) reasons.

In Australia (and the United States) Ozempic is approved to be used to improve blood glucose levels in adults with type 2 diabetes. By effectively managing blood glucose levels, the medicine goals to reduce the risk of great complications comparable to heart disease.

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Wegovy is approved to be used together with food plan and exercise for individuals who have a body mass index (BMI) of 30 or more, or 27 or more but produce other health conditions comparable to hypertension.

Wegovy can be utilized in people aged 12 and older. Like Ozempic, Wegovy is designed to reduce the risk of future health complications, including heart disease.

2) Both are injectable but are available in different concentrations.

Ozempic is on the market in disposable pens with pre-filled doses of 0.25 mg, 0.5 mg, 1 mg, or 2 mg per injection. The dose could be slowly increased to a maximum of two mg per week if needed.

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Wegovy is on the market in pre-filled disposable pens with doses of 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, or 2.4 mg. Treatment is initiated at a dose of 0.25 mg once per week for 4 weeks, after which the dose is steadily increased to a maintenance dose of two.4 mg per week.

While it’s unknown what impact the introduction of Wegovy can have on the availability of Ozempic, Ozempic continues to be available It is predicted that there might be few of them until the end of 2024.

Is Wegovy effective for weight reduction?

Considering that Wegovy is a semaglutide, there’s very strong evidence can assist people reduce weight and keep it off.

Recent test found that over 4 years, participants taking Wevovy as directed experienced a mean weight reduction of 10.2% of their body weight and a discount in waist circumference of seven.7 cm.

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Analyses showed that individuals who stopped taking the drug lost about two-thirds of their weight. recovered.

A man leans on the railing of a bridge
Wegovy can assist people reduce weight and keep it off – while taking the medication.
Mladen Mitrinovic/Shutterstock

What are the unwanted side effects of Wegova?

Most common unwanted side effects there’s nausea and vomiting.

However, other serious unwanted side effects are also possible due to the drug’s effects on the entire body. Thyroid tumors and cancer have been identified as risks in animal studies, but are rare in humans. scientific literature.

In the four-year-old Wegovy test16.6% of participants who received Wegovy (1,461 people) experienced an adversarial event that led to everlasting discontinuation of the drug. This was higher than 8.2% of participants (718 people) who received placebo (no energetic ingredient).

Side effects included gastrointestinal upset (including nausea and vomiting), which occurred in 10% of individuals taking Wegovy compared with 2% of individuals taking placebo.

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Gallbladder dysfunction occurred in 2.8% of individuals taking Wegovy and 2.3% of individuals taking placebo.

Recently, there have been concerns about suicidal thoughts and behaviors, global evaluation greater than 36 million adversarial event reports related to the use of semaglutide (Ozempic or Wegovy) since 2000 were reviewed.

There were 107 reports of suicidal thoughts and self-harm amongst people taking semaglutide, including, unfortunately, six actual deaths. When people stopped taking the drug, 62.5% said the thoughts stopped. We do not know if the dose, weight reduction, previous mental health conditions or use of antidepressants played a job.

There are also growing concerns about the negative impact of semaglutide on our social and emotional relationships with food. Thematic AND scientific evidence suggests that individuals taking semaglutide significantly reduce their every day food intake (as expected), skipping meals and avoiding social gatherings – which isn’t very nice for people and their family members.

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How can I access Wegovy?

Wegovy could be purchased at a pharmacy with a prescription from a health care provider.

But there’s a high price. Wegovy is currently not subsidized through the Pharmaceutical Benefits Scheme, leaving patients to bear the cost. The current cost is estimated at around 460 Australian dollars monthly dose.

If you’re considering Wegovy, arrange Consult your doctor for individual advice.

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This article was originally published on : theconversation.com
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Health and Wellness

The examination suggests that daily medicine can reduce the occurrence of cancer

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colorectal cancer


New study published in Journal of Clinical Oncology It suggests that a non -prescription joint drug can significantly reduce the risk of reoccurrence of colorectal cancer in patients previously diagnosed with disease.

In three years of research there have been 3,508 patients with colon cancer from stage I to III who underwent surgery. In the double -blind study, participants were randomly assigned to receive 160 mg aspirin or placebo. Scientists monitored patients to find out whether the medicine helped prevent refundable Cancer.

The results showed a major difference between two groups-a law, half of the patients who received aspirin experienced reduced reoccurrence of cancer over three years.

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“After three years of observation, the risk coefficients for recurrence comparing aspirin from placebo were 0.49 (95% CI; 0.24-0.98; p = 0.044) in group A and 0.42 (95% CI; 0.21-0.83; p = 0.013) in group B”, wrote the researchers.

Although further research is required, discoveries offer promise, especially for black Americans, who’re disproportionately affected by colorectal cancer. According to African Americans, there are about 20% more likely that colorectal cancer was diagnosed and about 40% more exposed to this in comparison with other racial and ethnic groups.

Experts assign these differences to several aspects, including lower indicators of screening, delayed diagnoses, limited access to top quality healthcare and structural inequalities in the medical system.

Although cancer in the rectum and colon are similar in some ways, their treatment may differ significantly. The rectum is in a limited space, strictly surrounded by other organs and structures, making surgery more complex. Often treatment of rectal cancer It covers surgery But it can also include chemotherapy, radiation or each. In some cases, targeted therapy or immunotherapy can also be really helpful.

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In 2024, it was expected that about 152,810 people in the USA were diagnosed with colorectal cancer with over 53,000 deaths. Public health leaders are still in favor of increased consciousness, early research and fair access to care to shut the survival gap to the endangered communities.

(Tagstotranslanter) Cancer

This article was originally published on : www.blackenterprise.com
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Health and Wellness

ICEM: Beyoncé’s Daisy Duke Blonde, Doechia’s button nails and more – essences

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Daisy Duke Blonde iCymil Beyoncé, nails for buttons and more

@Beyonce / Instagram

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Although this week couldn’t be assigned trends in celebrities last week, this week one thing cannot be said more: wet your hair. There is spring here, which implies that hydration and moisture is the largest trend, from wet curls to elegant chignons and water waves. Meanwhile, Coachella invites a brand new kind of admission to the most important festival stage, and beauty -like beauty has a brand new update (hint: Blush migrated).

Just every week before the Beyoncé route, she donated Daisy Duke Loierering in a restaurant with wet blond hair and denim nails to match her shorts. Similarly, the butt directed backwards, let’s examine its short, gel curls, turning natural textures right into a spring moment of beauty, while Anok Yai became even shorter in a cramped brown pix.

Doechia was like a doll fastened with buttons: pink blush of the attention, half braids micro-up and blue nails decorated with buttons. A glance supported by Amaarae, who was blushing, extending her corners in Coachelli, and then Ravyn Lenae in loose red water waves to his own festival set. Chignon Marsa Martin and Brzeg Josephine Baker in Esque meant business, closing every week with skilled elegance.

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If you missed this, take a look at the 13 best moments of the great thing about celebrities from the week.

This article was originally published on : www.essence.com
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Health and Wellness

Hidden health threats to the lip fillers

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Plump, fluffy lips They are in all places – From social media filters to red carpets celebrities. But for the shiny aesthetics of the lip fillers lies Growing fears amongst doctors.

Increasing the number of individuals in Great Britain – Often young women – select skin fillers to achieve a fuller appearance without surgery, a rise in filled “trout” and rigid “duck lips” caused a wave of alarm, Even amongst them which might normally support cosmetic procedures.

Lip filters are Far from risk -free – In some cases, health consequences are everlasting.

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Unlike surgical procedures, Lip filters will not be According to the law considered treatment. This implies that they’re largely unregulated, and in lots of cases they’re injected by individuals with little or any medical training.

https://www.youtube.com/watch?v=rynu4gd6Q0

This is an issue because the lips are delicate and highly mobile. They contain little or no natural fat and depend on the ring of small muscles to express every thing from joy to concern. Injection of an excessive amount of filler or using the flawed kind can interfere with these muscles – leaving the lips stiff, unnatural and even still.

While some patients are on the lookout for lip fillers Real medical causescomparable to face paralysis or distortion, these are exceptions. For the majority health threat It can prevail over cosmetic advantages.

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What are the fillers made from?

The substances utilized in lip fillers have modified over time. Older materials, comparable to liquid silicone, were finally withdrawn due to Serious complicationsincluding scars and product migration to other parts of the body.

Today, Most lip fillers are made from Hyaluronic acid (Ha) – a substance that naturally exists in our body, especially in connective tissue. Ha attracts water, giving the volume of the skin and maintaining its hydration. How we age Our natural HA levels are decreasingThat is why the skin becomes more dry and loses firmness.

Ha utilized in fillers is either extruded from animal tissue, for instance Covering the roosteror produced synthetically with bacteria. Although this contemporary version is safer than older fillers, it It still carries including allergic reactions, reactivation of cold wounds (common herpes virus), infections and inflammation.

There were also rare, but severe cases Vascular complications comparable to blindness and Death of tissuewhen fillers by accident enter blood vessels.

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Kidney risk

Less widely known – but equally disturbing – is how a repetitive filler can affect internal organsEspecially the kidneys.

Hyaluronic acid is just not only plum of the skin – it also plays a task In the immune system. When the body detects inflammation, for instance, from repeated filling injections, it might probably react, producing ha in the kidneys. This causes a series response: firstly, the kidneys produce a high molecular weight ha, which increases inflammation. Later they switch to low molecular weight ha, which reduces inflammation, but causes fibrosis or tissue scars.

This double -edged answer was related to chronic kidney disease, and even severe cases even kidney failure. Scientists are still studying these links, but the risk becomes more significant with every repeated injection – especially in people who find themselves genetically or medically.

https://www.youtube.com/watch?v=oloyiwkdini

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HA also can contribute to the creation of Calcium oxalate crystals in the kidneys. They can lead to kidney stones and further tissue damage, potentially causing lifelong complications.

Who should avoid lip fillers?

Given this risk, some people should approach fillers with extreme caution – or completely avoid them. These include individuals with problems with kidneys or allergic reactions to filling ingredients, recurrent cold wounds, autoimmune conditions (comparable to tools or rheumatoid arthritis), diabetes or blood clotting and pregnant women or breastfeeding.

Despite the risk of lip fillers, they continue to be widely available and strongly promoted – especially for young people under the influence of social media trends. Many undergo these treatments without fully understanding what they put into their bodies.

So what must change? First, higher adjustment. If the injections filling the lips were treated as medical procedures, more severe controls could help reduce unsuccessful treatment methods and serious complications.

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Secondly, more education. Patients must understand this only because something is “non -surgical”, doesn’t mean that it’s protected. Fillers are still injected with foreign substances into the body. They equip themselves with risk – and these risk can increase over time.

Lip filters can offer subtle, beautiful improvements when used sparingly and professionally. But after improper use or abuse, they will lead to everlasting distortion, lack of function and even serious internal health problems comparable to kidney damage.

Spicheum trends should never come at the expense of your health.

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This article was originally published on : theconversation.com
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