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What is ‘sloth fever’ and how can I avoid it when traveling to South America?

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International authorities are warning of “sloth fever.” Despite its name, you can’t catch it from sloths. Instead, it’s best to avoid contact with mosquitoes and biting midges.

So how can Australians protect themselves from sloth fever when traveling to South and Central America? And how does “sloth fever” compare to other mosquito-borne diseases like Zika?

What is sloth fever?

Sloth fever is attributable to Oropouche virus and is formally referred to as Oropouche viral disease or Oropouche fever.

The virus is orthobunyavirusIt due to this fact belongs to a special family of viruses than the flaviviruses (which include dengue, Japanese encephalitis and Murray Valley encephalitis viruses) and alphaviruses (chikungunya, Ross River virus and Barmah Forest virus).

Oropouche virus was first identified in 1955. It is named after the village in Trinidad and Tobago where the one that contracted it lived. first isolated from lived.

Symptoms include fever, severe headache, chills, muscle pain, joint pain, nausea, vomiting, and rash. This makes it difficult to distinguish it from other viral infections. About 60% of individuals infected get sick with the virus.

Is no specific treatment and most individuals get better in lower than a month.

However, serious symptomsincluding encephalitis and meningitis (inflammation of the brain and the membranes surrounding the brain and spinal cord) have been reported occasionally.

What is happening with this latest epidemic?

In July Pan American Health Organization issued a warning after two women from northeastern Brazil died from Oropouche virus infection, the primary death related to the virus.

There was also one fetal death, one miscarriage, and 4 cases of newborns with microcephaly, a condition characterised by an abnormally small head, that occurred while pregnant. This situation is paying homage to Zika virus outbreak in 2015–2016.

Oropouche has historically been a major problem in America. However, the disease lost its importance after subsequent outbreaks of the epidemic. chikungunya AND Zika from 2013 to 2016 and recently, dengue.

How does Oropouche virus spread?

Oropouche virus has has not been well researched compared to other insect-borne pathogens. We still don’t fully understand how the virus It’s spreading.

The virus is transmitted primarily by blood-sucking insects, particularly midges (especially ) and mosquitoes (potentially multiple species , , , and ).

We consider the virus circulates in forest areas, with primates, sloths, and birds being the essential suspected vectors. In urban outbreaks, humans are carriers of the virus, and blood-sucking insects infect others.

Share of midges (blood-sucking insects) in Australia they’re wrongly called “sand flies”) makes the transmission cycle of Oropouche virus somewhat different from that of viruses spread solely by mosquitoes. The kinds of insects that spread the virus may additionally differ between forested and urban areas.

Midges are much smaller than mosquitoes, but can still spread pathogens corresponding to Oropouche virus.
A/Prof Cameron Webb (Health Pathology NSW)

Why is Oropouche virus becoming more common?

Centers for Disease Control and Prevention (CDC) within the United States recently issued a warning on the growing cases of Oropouche in America. The variety of cases is increasing outside areas where it was previously found, corresponding to the Amazon basin, worrying authorities.

More than 8,000 cases of the disease have been reported in countries including Brazil, Bolivia, Peru, Colombia and Cuba.

There have been reports of travelers in Cuba and Brazil becoming infected after returning to the country. Europe AND North Americaappropriately.

While changing climate, deforestation and increased human movement may partly explain the rise in cases and the geographic spread of the virus, but there could also be something else at play.

Oropouche virus seems to have greater potential genomic reassortmentThis means the virus may evolve more rapidly than other viruses, potentially leading to more severe disease or increased transmission.

Other kinds of orthobunyaviruses have been shown to undergo genetic changes, cause more severe illness.

Should Australia be anxious?

Without more information on the role of local midges and mosquitoes within the spread of Oropouche virus, it is difficult to assess how great a risk it poses to Australia.

The risk of an infected traveller bringing the virus back to Australia is low. Very few cases of Zika have been reported in travellers from South or Central America return to Australia. Dengue is rarely reported from these travelers.

The biting insects most significant in spreading the virus in America are usually not present in Australia.

Although the chance is small, authorities need to concentrate on potentially infected travelers getting back from South and Central America and remember that appropriate test protocols to detect infection.

Australia has own local orthobunyaviruses Although these bacteria are known to cause infections, the health risk is considered to be low.

What can travellers do to protect themselves?

There are not any vaccines or specific treatments for Oropouche virus.

If you’re traveling to South and Central American countries, take appropriate steps to avoid mosquito and midge bites.

Mosquito repellents containing diethyltoluamide (DEET), picaridin, and lemon eucalyptus oil have been proven to be effective in reducing the results of mosquito bites and are expected to be effective against midge bites as well.

You can further reduce your risk by wearing long-sleeved shirts, long pants, and closed shoes.

Sleeping and resting under mosquito nets impregnated with insecticide will help, but you’ll need nets with much finer meshes, as midges are much smaller than mosquitoes.

Although Australian authorities haven’t issued any specific warnings, CDC AND European Centre for Disease Prevention and Control warn that pregnant women should discuss travel plans and potential risks with their doctor.



This article was originally published on : theconversation.com
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Health and Wellness

Jury awarded $310 million to parents of teenager who died after falling on a ride at Florida amusement park – Essence

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Sun Sentinel/Getty Images

The family of Tire Sampson, the 14-yr-old who tragically died on an amusement park ride in Orlando, Florida, in 2022, has been awarded $310 million in a civil lawsuit.

Tire, who was visiting ICON Park along with his family on March 24, 2022, fell from the FreeFall drop tower. Although he was taken to a nearby hospital, he didn’t survive his injuries.

Now, greater than two years later, a jury has held the vehicle manufacturer, Austria-based Funtime Handels, responsible for the accident and awarded the Tire family $310 million. According to reports from local news stations WFTV AND KSDKthe jury reached its verdict after about an hour of deliberation.

Tyre’s parents will each receive $155 million, according to attorney spokesman Michael Haggard.

Attorneys Ben Crump and Natalie Jackson, who represented Tyre’s family, shared their thoughts on this landmark decision via X (formerly Twitter). “This ruling is a step forward in holding corporations accountable for the safety of their products,” they said in a statement.

Lawyers stressed that Tyre’s death was attributable to “gross negligence and a failure to put safety before profits.” They added that the ride’s manufacturer had “neglected its duty to protect passengers” and that the substantial award ensured it could “face the consequences of its decisions.”

Crump and Jackson said they hope the result will encourage change throughout the theme park industry. “We hope this will spur the entire industry to enforce more stringent safety measures,” they said. “Tire heritage will provide a safer future for drivers around the world.”

An investigation previously found that Tyre’s harness was locked through the descent, but he dislodged from his seat through the 430-foot fall when the magnets engaged. Tire’s death was ruled the result of “multiple injuries and trauma.”

ICON Park said at the time that it could “fully cooperate” with the authorities.

This article was originally published on : www.essence.com
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Health and Wellness

Tireless HIV/AIDS advocate A. Cornelius Baker dies

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HIV/AIDS Advocate, A. Cornelius Baker


A. Cornelius Baker, a tireless advocate of HIV and AIDS testing, research and vaccination, died Nov. 8 at his home in Washington, D.C., of hypertensive, atherosclerotic heart problems, in response to his partner, Gregory Nevins.

As previously reported, Baker was an early supporter for people living with HIV and AIDS within the Nineteen Eighties, when misinformation and fear-mongering in regards to the disease were rampant.

According to Douglas M. Brooks, director of the Office of National AIDS Policy under President Obama, it was Baker’s Christian faith that guided him toward compassion for others.

“He was very kind, very warm and inclusive – his circles, both professional and personal, were the most diverse I have ever seen, and he was guided by his Christian values,” Brooks told the outlet. “His ferocity was on display when people were marginalized, rejected or forgotten.”

In 1995, when he was executive director of the National AIDS Association, Baker pushed for June 27 to be designated National HIV Testing Day.

In 2012, he later wrote on the web site of the Global Health Advisor for which he was a technical advisor that: “These efforts were intended to help reduce the stigma associated with HIV testing and normalize it as part of regular screening.”

https://twitter.com/NBJContheMove/status/1856725113967632663?s=19

Baker also feared that men like himself, black gay men, and other men from marginalized communities were disproportionately affected by HIV and AIDS.

Baker pressured the Clinton administration to incorporate black and Latino people in clinical drug trials, and in 1994 he pointedly told the Clinton administration that he was bored with hearing guarantees but seeing no motion.

According to Lambda Legal CEO Kevin Jennings, yes that daring attitude that defines Baker’s legacy in the world of ​​HIV/AIDS promotion.

“Cornelius was a legendary leader in the fight for equality for LGBTQ+ people and all people living with HIV,” Jennings said in a press release. “In the more than twenty years that I knew him, I was continually impressed not only by how effective he was as a leader, but also by how he managed to strike the balance between being fierce and kind at the same time. His loss is devastating.”

Jennings continued: “Cornelius’ leadership can’t be overstated. For many years, he was one in all the nation’s leading HIV/AIDS warriors, working locally, nationally and internationally. No matter where he went, he proudly supported the HIV/AIDS community from the Nineteen Eighties until his death, serving in various positions including the Department of Health and Human Services, the National Association of Persons with Disabilities AIDS, and the Whitman-Walker Clinic . Jennings explained.

Jennings concluded: “His career also included several honors, including being the first recipient of the American Foundation for AIDS Research Foundation’s organization-building Courage Award. Our communities have lost a pillar in Cornelius, and as we mourn his death, we will be forever grateful for his decades of service to the community.”

Kaye Hayes, deputy assistant secretary for communicable diseases and director of the Office of Infectious Diseases and HIV/AIDS Policy, in her comment about his legacy, she called Baker “the North Star.”.

“It is difficult to overstate the impact his loss had on public health, the HIV/AIDS community or the place he held in my heart personally,” Hayes told Hiv.gov. “He was pushing us, charging us, pulling us, pushing us. With his unwavering commitment to the HIV movement, he represented the north star, constructing coalitions across sectors and dealing with leaders across the political spectrum to deal with health disparities and advocate for access to HIV treatment and look after all. He said, “The work isn’t done, the charge is still there, move on – you know what you have to do.” It’s in my ear and in my heart in the case of this job.

Hayes added: “His death is a significant loss to the public health community and to the many others who benefited from Cornelius’ vigilance. His legacy will continue to inspire and motivate us all.”

Baker is survived by his mother, Shirley Baker; his partner Nevins, who can be senior counsel at Lambda Legal; his sisters Chandrika Baker, Nadine Wallace and Yavodka Bishop; in addition to his two brothers, Kareem and Roosevelt Dowdell; along with the larger HIV/AIDS advocacy community.


This article was originally published on : www.blackenterprise.com
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Health and Wellness

Bovaer is added to cow feed to reduce methane emissions. Does it pass into milk and meat? And is it harmful to humans?

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There are growing concerns in regards to the use of feed supplements, Bowar 10to reduce methane production in cows.

Bovaer 10 consists of silicon dioxide (mainly sand), propylene glycol (food stabilizer approved by Food Safety Australia New Zealand) and lively substance 3-nitrooxypropanol (3-NOP).

There has been an enormous amount of misinformation in regards to the safety of 3-NOP, with some milk from herds fed this additive being labeled “Frankenmilk”. Others feared it could get to humans through beef.

The most significant thing is that 3-NOP is secure. Let’s clear up some major misconceptions.

Why do we want to limit methane production?

In our attempts to limit global warming, we’ve placed the best emphasis on CO₂ because the major man-made greenhouse gas. But methane is also a greenhouse gas, and although we produce less of it, it is: a much stronger greenhouse gas than CO₂.

Agriculture is the largest a man-made source of methane. As cattle herds expand to meet our growing demand for meat and milk, reducing methane production from cows is a vital way to reduce greenhouse gas emissions.

There are several ways to do that. Stopping bacteria within the stomachs of cows that produce methane one approach is to produce methane.

The methane produced by cows and sheep doesn’t come from the animals themselves, but from the microbes living of their digestive systems. 3-NO stop the enzymes that perform the last step of methane synthesis in these microorganisms.

3-NOP is not the one compound tested as a feed additive. Australian product based on seaweed, Rumin8for instance, it is also in development. Saponins, soap-like chemicals present in plants, and essential oils as well has been examined.

However, 3-NOP is currently one of the popular effective treatments.

Nitrooxypropanol structure: red balls are oxygen, gray carbon, blue nitrogen and white hydrogen.
PubChem

But is not it poison?

There are concerns on social media that Bovaer is “poisoning our food.”

But, as we are saying in toxicology, it’s the dose that makes the poison. For example, arsenic is deadly 2–20 milligrams per kilogram of body weight.

In contrast, 3-NOP was not lethal on the doses utilized in safety studies, up to 600 mg 3-NOP per kg body weight. At a dose of 100 mg per kg body weight in rats, it didn’t cause any adversarial effects.

What about reproductive issues?

The effect of 3-NOP on the reproductive organs has generated numerous commentary.

Studies in rats and cows showed that doses of 300–500 mg per kg body weight caused: contraction of the ovaries and testicles.

In comparison, to achieve the identical exposure in humans, a 70 kg human would want to eat 21–35 grams (about 2 tablespoons) of pure 3-NOP every day for a lot of weeks to see this effect.

No human will likely be exposed to this amount because 3-NOP doesn’t pass into milk – is fully metabolized within the cow’s intestines.

No cow will likely be exposed to these levels either.

The cow licks itself
Cows will not be exposed to levels tested on animals in laboratory studies.
Ground photo/Shutterstock

What about cancer?

3-NOP is not genotoxic or mutagenicwhich implies it cannot damage DNA. Thus, the results of 3-NOP are dose-limited, meaning that small doses will not be harmful, while very high doses are (unlike radiation where there is no secure dose).

Scientists found that at a dose of 300 mg per kilogram of body weight benign tumors of the small intestine of female ratsbut not male rats, after 2 years of every day consumption. At a dose of 100 mg 3-NOP per kg body weight, no tumors were observed.

Cows eat lower than 2 grams of Bovaer 10 per day (of which only 10% or 0.2 grams is 3-NOP). This is about 1,000 times lower than the appropriate every day intake 1 mg 3-NOP per kg body weight per day for a cow weighing 450 kg.

This level of consumption will likely be not the result in cancer or any of them other adversarial effects.

So how much are people exposed to?

Milk and meat consumers will likely be exposed to zero 3-NOP. 3-NOP doesn’t penetrate milk and meat: is completely metabolized within the cow’s intestines.

Farmers could also be exposed to small amounts of the feed additive, and industrial employees producing 3-NOP will potentially be exposed to larger amounts. Farmers and industrial employees already wear personal protective equipment to reduce exposure to other agricultural chemicals – and it is advisable to do that with Bovear 10 as well.

Milk
3-NOP doesn’t penetrate milk and meat.
Shutterstock

How widely has it been tested?

3-NOP has been in development for 15 years and has been subject to multiple reviews by European Food Safety Authority, UK Food Safety Authority AND others.

It has been extensively tested over months of exposure to cattle and has produced no unintended effects. Some studies actually say so improves the standard of milk and meat.

Bovaer was approved for use in dairy cattle by the European Union from 2022 and Japan in 2024. It is also utilized in many other countries, including: in beef products, amongst others Australia.

A really small amount of 3-NOP enters the environment (lower than 0.2% of the dose taken), no accumulates and is easily decomposed subsequently, it doesn’t pose a threat to the environment.

Since humans will not be exposed to 3-NOP through milk and meat, long-term exposure is not an issue.

What does Bill Gates have to do with this?

Bill Gates has invested in a distinct feed processing method for methane, Australian seaweed-based Rumin8. But he has nothing to do with Bovaer 10.

The Bill & Melinda Gates Foundation awarded research grants to the corporate producing 3-NOP for malaria control researchnot for 3-NOP.

The bottom line is that adding 3-NOP to animal feed doesn’t pose any risk to consumers, animals or the environment.

This article was originally published on : theconversation.com
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