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Ovarian cancer is difficult to detect. Focusing on these 4 symptoms can help with diagnosis

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Ovarian cancer is often detected when it is already at a sophisticated stage and difficult to treat.

Scientists I even have believed for a very long time this was because women first experienced symptoms when the ovarian cancer was already well advanced. Symptoms can even be It is difficult to discover because they’re vague and similar to other conditions.

But recent study shows promising signs that ovarian cancer can be detected early. The study checked out women with 4 specific symptoms – bloating, abdominal pain, a frequent need to urinate and a fast feeling of fullness – and put them on the fast track to a specialist.

This signifies that even essentially the most aggressive types of ovarian cancer can be detected at an early stage.

So what did the study show? And what could it mean for faster detection – and treatment – ​​of ovarian cancer?

Why is ovarian cancer difficult to detect early?

Ovarian cancer can’t be detected through cervical cancer screening (formerly called Pap smears) and pelvic exams are usually not useful as a screening test.

Current Australian Guidelines We recommend that ladies be tested for ovarian cancer in the event that they have symptoms over a month. But lots of symptoms – similar to fatigue, constipation and changes in menstrual cycles – are vague and overlap with symptoms of other common illnesses.

This makes early detection a challenge. But it is crucial – woman possibilities of surviving ovarian cancer have to do with how advanced the cancer is on the time of diagnosis.

Symptoms of ovarian cancer can include bloating, abdominal pain, and feeling full quickly after starting to eat.
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If the cancer is still confined to the unique site and has not spread, the five-year survival rate is 92%. However, greater than half of ladies diagnosed with ovarian cancer don’t develop symptoms until after the disease has progressed. already metastasizedwhich suggests it has spread to other parts of the body.

If the cancer has spread to nearby lymph nodes, the survival rate drops to 72%. If the cancer has already metastasized and spread to distant sites on the time of diagnosis, the speed is just 31%.

There are mixed results on whether earlier detection of ovarian cancer leads to higher survival rates. For example, a UK study that examined greater than 200,000 women failed to reduce the variety of deaths.

That study screened most of the people somewhat than relying on self-reported symptoms. The recent study suggests that asking women to search for specific symptoms could lead on to earlier diagnosis, meaning treatment could start sooner.

What did the brand new study focus on?

Between June 2015 and July 2022, researchers recruited 2,596 women aged 16 to 90 from 24 UK hospitals.

They were asked to monitor the next 4 symptoms:

  • persistent abdominal bloating (women often call it flatulence)
  • feeling full soon after starting to eat and/or lack of appetite
  • pelvic or abdominal pain (which can feel like indigestion)
  • urgent or more frequent need to urinate.

Women who reported not less than considered one of the 4 symptoms persistently or regularly were included fast track. This means they were sent to see a gynaecologist inside two weeks. Fast-track has been utilized in the UK since 2011, but is not a part of the Australian guidelines.

About 1,741 participants were placed on this fast track. First, that they had a blood test that measured cancer antigen 125 (CA125). If a girl’s CA125 level was abnormal, she was sent for an internal vaginal ultrasound.

What did they find?

The study suggests that this process is higher at detecting ovarian cancer than general screening of people that haven’t any symptoms. About 12% of ladies on the fast track were diagnosed with some kind of ovarian cancer.

A complete of 6.8% of fast-track patients were diagnosed with high-grade serous ovarian cancer. This is essentially the most aggressive type of cancer, accounting for 90% of ovarian cancer deaths.

Among women with essentially the most aggressive form, one in 4 were diagnosed when the cancer was still in its early stages. This is vital since it allowed the deadliest cancer to be treated before it had spread significantly throughout the body.

There were some promising signs in treating people with this aggressive form. Most (95%) underwent surgery, and three-quarters (77%) underwent chemotherapy. Complete cytoreduction—meaning the entire cancer had been removed—was achieved in six of 10 women (61%).

This is a promising sign that there could also be ways to “detect” and treat ovarian cancer before it has a probability to recover established within the body.

What does this mean for detection?

The study results suggest that this approach to early testing and referral for symptoms leads to earlier detection of ovarian cancer. It may improve outcomes, although the study didn’t track survival rates.

It also highlights the importance of public awareness of the symptoms.

Doctors should find a way to recognize all of the symptoms of ovarian cancer, including vague symptoms similar to general fatigue.

However, enabling most of the people to recognize a narrower set of 4 symptoms may help us begin diagnosing, detecting, and treating ovarian cancer sooner than we thought.

This would mean that GPs wouldn’t have to recommend testing for ovarian cancer to every woman who feels generally drained or constipated, making diagnosis and treatment more targeted and effective.

Many women remain (*4*)unaware of the symptoms ovarian cancer. This study shows that recognizing them can help with early detection and treatment.

This article was originally published on : theconversation.com
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Health and Wellness

In the USA, bird flu was detected in pigs. Why does this matter?

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Last week, the U.S. Department of Agriculture reported that a pig at a backyard farm in Oregon had been infected with bird flu.

As the bird flu situation continues to evolve, now we have learned that the A/H5N1 strain of the virus infects a spread of animals, including quite a lot of birds, wildlife and dairy cattle.

Fortunately, now we have not seen sustained spread of the virus between people at this stage. However, the detection of the virus in pigs represents a worrying development in the trajectory of this virus.

How did we get here?

The most concerning sort of bird flu currently circulating is clade 2.3.4.4b A/H5N1, the influenza A strain.

Since 2020, the A/H5N1 2.3.4.4b virus has spread to a big selection of birds, wildlife and livestock which have never previously been infected with avian influenza.

While Europe is a hotspot for A/H5N1, attention is currently focused on the US. In 2024, dairy cattle were infected for the first time, with over The problem affects 400 herds in a minimum of 14 US states.



Bird flu has huge consequences for breeding and industrial food production, as infected poultry flocks should be slaughtered and infected cows may result in contamination dairy products. That said, pasteurization should make the milk secure to drink.

Although farmers have suffered heavy losses as a consequence of H5N1 bird flu, it may well also mutate to cause a pandemic in humans.

Birds and humans have various kinds of receptors in their respiratory tract to which influenza viruses attach, corresponding to a lock (receptors) and a key (virus). The attachment of the virus allows it to enter the cell and body and cause disease. Avian influenza viruses are adapted to birds and spread easily amongst birds but not in humans.

So far, human cases have mainly occurred in individuals who stayed at the facility close contact with infected livestock or birds. In the US, the majority were agricultural employees.

The fear is that the virus will mutate and adapt to humans. One key step for this to occur could be to vary the virus’s affinity from bird receptors to receptors found in the human respiratory tract. In other words, if the virus “key” has mutated to raised fit the human “lock”.

Recent testing of sample A/H5N1 2.3.4.4bz infected person, disturbing results were obtainedidentifying mutations in the virus which will increase transmission between human hosts.

Why are pigs an issue?

A pandemic strain of influenza in humans can arise in several ways. One involves close contact between humans and animals infected with their very own specific influenza viruses, creating opportunities mixing of genes of avian and human viruses.

Pigs are the perfect vessel for mixing genes to supply a human strain of pandemic flu because they’ve receptors in their respiratory tract that each avian and human influenza viruses it may well get tied up.

This signifies that pigs will be infected with each avian influenza virus and human influenza virus. These viruses can exchange genetic material, mutate and simply transmit to humans.


Conversation, CC BY-SA

Interestingly, there have been pigs in the past less vulnerable to A/H5N1 viruses. However, the virus has recently mutated they infect pigs more easily.

In a recent case in Oregon, A/H5N1 was detected in a pig on a non-commercial farm following an outbreak of disease amongst poultry kept on the same holding. This A/H5N1 strain originated from wild birdsand never the one common in US dairy cows.

Pig infection is a warning. If the virus makes its way into industrial piggeries, it might create a much higher level of pandemic risk, especially as winter approaches in the U.S., when seasonal human flu cases begin to extend.



How can we minimize the risk?

Surveillance is vital to early detection of a possible pandemic. This includes comprehensive testing and reporting of infections in birds and animals financial compensation and support measures for farmers to encourage timely reporting.

Strengthening global surveillance of influenza is crucial because unusual spikes in pneumonia and severe respiratory illnesses could signal a human pandemic. Our EPIWATCH system looks for early warnings of such activity, which can accelerate vaccine development.

If a cluster of human cases occurs and influenza A is detected, further testing (called subtyping) is vital to find out whether it’s a seasonal strain, an avian strain resulting from transmission of the virus, or a brand new pandemic strain.

Early identification can prevent a pandemic. Any delay in identifying an emerging pandemic strain allows the virus to spread widely across international borders.

The first human case of A/H5N1 in Australia was in a baby who became infected while traveling in India and was hospitalized for the disease in March 2024. Tests then identified influenza A (which might have been seasonal influenza or bird flu), but subtype to discover A/H5N1 was delayed.

This sort of delay may very well be costly if human-borne A/H5N1 emerges and is taken into account seasonal influenza because the influenza A test is positive. 5% of positive tests for influenza A undergo further subtyping in Australia and most countries.

In light of the current situation, there needs to be a low threshold for subtyping influenza A strains in humans. Rapid tests that may tell the difference between seasonal flu and H5 A flu are emerging and may form a part of governments’ pandemic preparedness.

The risk is higher than ever before

The U.S. Centers for Disease Control and Prevention states that the current risk posed by H5N1 to the general public stays low.

However, with the H5N1 virus already in a position to infect pigs and showing worrying mutations in adapting to humans, the risk level has increased. Given that the virus is so common amongst animals and birds, the statistical probability of a pandemic is higher than ever before.

The excellent news is that we’re higher prepared for a flu pandemic than other pandemics because vaccines will be produced in the same way as seasonal flu vaccines. Once the genome of the pandemic flu virus is understood, vaccines will be updated to match it.

Partially matched vaccines and a few are already available countries corresponding to Finland vaccinate high-risk farm employees.

This article was originally published on : theconversation.com
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Health and Wellness

WATCH: Joshua Joseph What kind of America do we want to be? – Essence

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“; } }); // Drag and scroll functionality const playlistContainer = document.getElementById(‘playlist’); let isDown = false; let startY; let scrollTop; playlistContainer.addEventListener(‘mousedown’, (e) => { isDown = true; playlistContainer.classList.add(‘active’); startY = e.pageY – playlistContainer.offsetTop = playlistContainer.addEventListener(‘mouseleave’; playlistContainer.classList.remove(‘active’); playlistContainer.addEventListener(‘mouseup’, () => { isDown = false; playlistContainer.classList.remove(‘active’); }); mousemove’, (e) => { if (!isDown) return; e.preventDefault(); const y = e.pageY – playlistContainer.offsetTop; const walk = (y – startY) * 3; .scrollTop = scrollTop – walk; }); } } if (” !== ‘efoc24’) { // Check DoubleVerify Quality Targeting signals before rendering the player if ( ‘unknown’ !== typeof PQ ) { PQ.cmd. push(function() { // If DVQT signals are not available after 500 ms, render the player anyway. const timeout_id = setTimeout( jwPlayerRender, 500 ); // Get “Authentic Direct” signals. PQ.getTargeting({ signals: [‘abs’] }, function(error, targetingData) { clearTimeout(timeout_id); jwPlayerRender(error? undefined: targetingData); }); }); } else { jwPlayerRender(); } function jwPlayerRender( dvqt_signals=”” ) { let jw_ad_tag ​​= {“client”:”googima”,”adscheduleid”:”G7hR9pQ2″,”schedule”:[{“tag”:”https://pubads.g.doubleclick.net/gampad/ads?correlator=&iu=/21698916284/ess/VideoNews&env=vp&gdfp_req=1&output=vast&sz=400×300%7C640x480%7C1000x1%7C1920x1080&description_url=__page-url__&tfcd=0&npa=0&vpmute=1&vpa=auto&vad_type=linear&url=__page-url__&vpos=preroll&unviewed_position_start=1&v=SRYaJJB3&pmnd=0&pmxd=60000&ad_rule=1&cust_params=ttid%3DSRYaJJB3%26frnch%3D__item-franchise__%26environment%3Dproduction%26kwblock%3DAbb%2CCapOne%2CLincoln%2CUPS%2CVG%2CATTCric%2CDisney”,”offset”:”pre”},{“tag”:”https://vid.springserve.com/vast/670880?url=https://www.essence.com/news/watch-joshua-jospeh-what-type-of-america-do-we-want-to-be/h=450&w=800&cb=2033″,”offset”:”50%”}]”offers”:{“bidders”:[{“id”:”jw-video-SRYaJJB3″,”name”:”jwdemand”,”publisherId”:”evcxFIDZ”,”siteId”:”WT5iFegj”,”placementId”:”24399785″}]”settings”:{“disableConsentManagementOnNoCmp”:true,”mediationLayerAdServer”:”dfp”,”floorPriceCents”:200,”floorPriceCurrency”:”usd”,”buckets”:[{“increment”:0.1,”max”:30,”min”:0},{“increment”:0.5,”max”:50,”min”:30}]}}}; // Configure ad tag on the fly… let additional_params = {}; // Input DVQT signals. if ( dvqt_signals && dvqt_signals.ABS.length > 0 ) { additional_params.ABS = dvqt_signals.ABS.join(“,”); } // Create a string of additional_parameters. let extra_params_str=””; for (enter additional_parameters) { let value = additional_parameters[key]; additional_params_str += `${key}=${value}`; if ( key !== Object.keys( additional_params .pop() ) { additional_params_str += ‘&’; } } // Update ad tag cust_params (must be URL encoded). if ( Object.keys( additional_parameters ). length > 0 ) { let ad_schedule = jw_ad_tag.schedule; if ( ‘undefined’ !== ad schedule type ) { for (let i = 0; i < ad_schedule. length; i++) { let address_address = new URL(jw_ad_tag. schedule[i].label); let query_params = new URLSearchParams(ad_url.search); query_params.set("cust_params", query_params.get("cust_params") + `&${additional_params_str}`); ad_url.search = query_params.toString(); jw_ad_tag.schedule[i].tag = ad_url.toString(); } } } let playerId; if ("undefined" !== type jwplayerQueue) { playerId = 'jw-video-SRYaJJB3'; jwplayerQueue.push({ 'instanceId': 'playerInstance_SRYaJJB3', 'playerId': playerId, 'config': { pid: 't6KP9zcV', playlist: "https://cdn.jwplayer.com/v2/media/SRYaJJB3", autostart: !jw_ad_tag, repeat: true, mute: true, aspect ratio: "16:9", share: {sites: ["facebook", "twitter", "email", "linkedin"]}, cast: {}, float: {disibility: true}, autoPause: {viewability: true}, displaytitle: true, displaydescription: true, controls: true, related: {displayMode: 'shelfWidget'}, interactive: {} , ad: jw_ad_tag ​​​​} }); } // Load video. jQuery(window).trigger("jw:loadplayers"); function waitForJWPlayer(callback) { if (type jwplayer !== 'undefined') { callback(); } else { setTimeout(function() { waitForJWPlayer(callback); }, 500); } } waitForJWPlayer(function() { jwplayer(playerId).on('adsManager', function (adsManagerLoaded) { let adsManager = adsManagerLoaded.adsManager; let videoElement = document.getElementById(playerId ); let config = { anId: '929481' , campId: '640x360', ias_xps: "autoplay", // autoplay state ias_xbp: "2", // video destination type ias_xar: "1" // autoplay state } // Start IAS integration googleImaVansAdapter. init(google, adsmanager, videoitem, config } } });

This article was originally published on : www.essence.com
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Health and Wellness

Primary care involves more than primary care physicians. A new review shows how patients can gain better access to healthcare

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Today there are Australians more likely than previous generations suffered from complex and chronic diseases similar to diabetes, heart disease and depression.

This means they’re more likely to need health care from a wide range of providers, similar to nurses, podiatrists, psychologists and physiotherapists, in addition to general practitioners. This is named “multidisciplinary care”. It works best when the abilities of all these professions can be found to the patient in a coordinated way.

However, the role of the health professions and how they’re financed have been frozen in laws and policy for a long time. All changes are gradual and chaotic. This mainly involved adding more items to the Medicare schedule, with each specialist practicing individually.

The result was greater inequality of access. Because less than half Alliance visits are billed collectively, with most patients paying almost A$70 for every consultation, and sometimes much more. Those who cannot afford the out-of-pocket costs and can’t discover a bulk invoicing specialist are missing out.

To assess how the federal government can remove barriers to team-based care and ensure healthcare employees achieve their full potential or full ‘scope of practice’, the federal government commissioned an independent review last yr.

The final report published yesterday sets a new path for primary care employees. This will make multidisciplinary care accessible to all Australians.

Utilizing the total potential of healthcare employees

The review included extensive consultations, including on two issues papers. The report itself comprises feedback from the consultation, including skeptical comments reflecting differences of opinion.

The title of the report was reflected, Unlocking the potential of our healthcare employeesits primary focus is on changing the foundations and regulations imposed by state and federal governments. This makes the work of healthcare employees more difficult and limits their ability to use their full skills and knowledge to manage patient care.

Over the past a long time the education of health care employees has improved. Professionals are subsequently able to do more than before. However, rules and regulations haven’t progressed, making it difficult for professionals to share these skills and knowledge.

The review found that that is contributing to profession dissatisfaction and other people leaving a wide range of health professions, exacerbating workforce shortages.

The review proposes a new way of documenting and describing what a occupation can do, through a so-called national skills and capabilities framework and matrix.

As with many other recommendations, the review highlights where that is already getting used internationally and how it can be integrated into other policies and frameworks to help with implementation.

Health care employees don’t use all their skills.
Studio DC/Shutterstock

To the frustration of most allied health professions, the review doesn’t recommend greater Medicare payments to allow them to practice independently.

Rather, the review beneficial paying for general practices to develop multidisciplinary teams. This will help professionals collaborate moderately than compete or isolate themselves.

The review also beneficial changing the foundations on healthcare skilled referrals, allowing qualified healthcare professionals to refer directly to non-GP specialists in similar areas. This signifies that if mandatory, your psychologist can refer you directly to a psychiatrist, or your physiotherapist can refer you directly to an orthopedic surgeon, moderately than going back to your GP.

This will weaken the GP’s gatekeeper role and potentially undermine the more holistic care provided by GPs. However, from the patient’s viewpoint, eliminating the intermediate step saves him/her out-of-pocket expenses.

The necessary suggestion recognizes that the health care system is evolving and that policies and regulations must evolve as well. It is subsequently now complementing its recommendations for change by introducing a continuous review approach through an independent mechanism. This would supply evidence-based advice and proposals on:

  • significant workforce innovations
  • new roles in health care
  • workforce models that involve a major change in scope.

When will we see change?

The review outlined a loose implementation timeline that might be described as short, medium and long run. It also assigns responsibility for every element of its recommendations to the suitable authorities and governments.

As almost all the recommendations require legislative changes, and lots of of them require agreement between the Commonwealth and the states, it’s unlikely that any of the changes will come into force this financial yr.

The review beneficial making changes in a scientific, evidence-based and protected way. Implementation would begin in areas of best need, similar to rural and distant Australia, in addition to in practices most ready for change, similar to Aboriginal Controlled Community Health Organizations or Victoria Community Health Centres.

The man is waiting for the doctor
The review beneficial changes to the referral process.
Voronaman/Shutterstock

IN releasing Health Minister Mark Butler described it as a “landmark” report and noted the complexity of implementation, which might require joint motion with states and territories. He noted the necessity for further consultations, but nevertheless adopted a supportive tone.

Can this review speed up real health reform?

Overall, the review found a pleased medium between giving healthcare employees the liberty to act and the stringent and inappropriate rules and regulations that currently limit patient care. It also outlines practical steps to achieve your goals.

The only drawback of the report is the emphasis on harmonizing state and territorial approaches. This would replace the present approach under which each state and territory decides, for instance, which vaccines can be administered by which specialists and which pharmacists can dispense over-the-counter.

One of the advantages of a federation is the potential for state and territory innovation and cross-border learning. Harmonization will limit such experimentation and will lead to greater stagnation seen previously in medical expert policy.

This article was originally published on : theconversation.com
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