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Ovarian cancer is difficult to detect. Focusing on these 4 symptoms can help with diagnosis

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Ovarian cancer is often detected when it is already at a sophisticated stage and difficult to treat.

Scientists I even have believed for a very long time this was because women first experienced symptoms when the ovarian cancer was already well advanced. Symptoms can even be It is difficult to discover because they’re vague and similar to other conditions.

But recent study shows promising signs that ovarian cancer can be detected early. The study checked out women with 4 specific symptoms – bloating, abdominal pain, a frequent need to urinate and a fast feeling of fullness – and put them on the fast track to a specialist.

This signifies that even essentially the most aggressive types of ovarian cancer can be detected at an early stage.

So what did the study show? And what could it mean for faster detection – and treatment – ​​of ovarian cancer?

Why is ovarian cancer difficult to detect early?

Ovarian cancer can’t be detected through cervical cancer screening (formerly called Pap smears) and pelvic exams are usually not useful as a screening test.

Current Australian Guidelines We recommend that ladies be tested for ovarian cancer in the event that they have symptoms over a month. But lots of symptoms – similar to fatigue, constipation and changes in menstrual cycles – are vague and overlap with symptoms of other common illnesses.

This makes early detection a challenge. But it is crucial – woman possibilities of surviving ovarian cancer have to do with how advanced the cancer is on the time of diagnosis.

Symptoms of ovarian cancer can include bloating, abdominal pain, and feeling full quickly after starting to eat.
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If the cancer is still confined to the unique site and has not spread, the five-year survival rate is 92%. However, greater than half of ladies diagnosed with ovarian cancer don’t develop symptoms until after the disease has progressed. already metastasizedwhich suggests it has spread to other parts of the body.

If the cancer has spread to nearby lymph nodes, the survival rate drops to 72%. If the cancer has already metastasized and spread to distant sites on the time of diagnosis, the speed is just 31%.

There are mixed results on whether earlier detection of ovarian cancer leads to higher survival rates. For example, a UK study that examined greater than 200,000 women failed to reduce the variety of deaths.

That study screened most of the people somewhat than relying on self-reported symptoms. The recent study suggests that asking women to search for specific symptoms could lead on to earlier diagnosis, meaning treatment could start sooner.

What did the brand new study focus on?

Between June 2015 and July 2022, researchers recruited 2,596 women aged 16 to 90 from 24 UK hospitals.

They were asked to monitor the next 4 symptoms:

  • persistent abdominal bloating (women often call it flatulence)
  • feeling full soon after starting to eat and/or lack of appetite
  • pelvic or abdominal pain (which can feel like indigestion)
  • urgent or more frequent need to urinate.

Women who reported not less than considered one of the 4 symptoms persistently or regularly were included fast track. This means they were sent to see a gynaecologist inside two weeks. Fast-track has been utilized in the UK since 2011, but is not a part of the Australian guidelines.

About 1,741 participants were placed on this fast track. First, that they had a blood test that measured cancer antigen 125 (CA125). If a girl’s CA125 level was abnormal, she was sent for an internal vaginal ultrasound.

What did they find?

The study suggests that this process is higher at detecting ovarian cancer than general screening of people that haven’t any symptoms. About 12% of ladies on the fast track were diagnosed with some kind of ovarian cancer.

A complete of 6.8% of fast-track patients were diagnosed with high-grade serous ovarian cancer. This is essentially the most aggressive type of cancer, accounting for 90% of ovarian cancer deaths.

Among women with essentially the most aggressive form, one in 4 were diagnosed when the cancer was still in its early stages. This is vital since it allowed the deadliest cancer to be treated before it had spread significantly throughout the body.

There were some promising signs in treating people with this aggressive form. Most (95%) underwent surgery, and three-quarters (77%) underwent chemotherapy. Complete cytoreduction—meaning the entire cancer had been removed—was achieved in six of 10 women (61%).

This is a promising sign that there could also be ways to “detect” and treat ovarian cancer before it has a probability to recover established within the body.

What does this mean for detection?

The study results suggest that this approach to early testing and referral for symptoms leads to earlier detection of ovarian cancer. It may improve outcomes, although the study didn’t track survival rates.

It also highlights the importance of public awareness of the symptoms.

Doctors should find a way to recognize all of the symptoms of ovarian cancer, including vague symptoms similar to general fatigue.

However, enabling most of the people to recognize a narrower set of 4 symptoms may help us begin diagnosing, detecting, and treating ovarian cancer sooner than we thought.

This would mean that GPs wouldn’t have to recommend testing for ovarian cancer to every woman who feels generally drained or constipated, making diagnosis and treatment more targeted and effective.

Many women remain (*4*)unaware of the symptoms ovarian cancer. This study shows that recognizing them can help with early detection and treatment.

This article was originally published on : theconversation.com
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Health and Wellness

Many people in the Pacific do not have access to adequate toilets, and climate change is making the situation worse.

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The Pacific Islands may conjure up images of vast coastlines and picturesque landscapes. But while this a part of the world may seem like paradise, many locals face a serious public health problem.

By Pacific Nationsalmost half one million people they live in informal urban settlements that lack adequate sanitation, which can result in limited access to functioning toilets.

This has an impact on health, well-being, education and livelihoods, especially for girlschildren, elderly people and disabled people.

Our recent study published in the journal Nature Pure water NPJWe examined the state of sanitation in several informal urban settlements in two Pacific countries – Fiji and Vanuatu. Our findings show that this is an issue that requires urgent attention.

Field research

We worked with researchers from the University of the South Pacific to survey households and examine sanitation infrastructure. Our team surveyed 393 households in nine informal urban settlements in the capitals of Fiji (Suva) and Vanuatu (Port Vila).

These housing estates are developing when people decide on uninhabited land that has not been planned for development, often due to a scarcity of reasonably priced housing options. Informal urban settlements often lack access to basic services and infrastructure, corresponding to sewage systems, electricity, paved roads and waste collection.

We found that although piped water is available, the majority of households (between 56% and 100% of households in each settlement) still depend on unsafe sanitation to manage human waste. Many use poorly constructed dry pits – for instance, a plinth over a hole in the ground – or cesspools. These toilets have no plumbing and do not use running water for flushing. All are positioned on-site (in or near the home), meaning that waste, treated or untreated, stays in the settlement.

Our team inspected sanitation infrastructure in nearly 400 households in Vanuatu (pictured) and Fiji.
Benny Zuse Rousso

In addition to on a regular basis challenges, we found that one in three households loses access to functioning toilets during heavy rains, cyclones or floods. Dry well systems are 4 to eight times more likely to be damaged during climate events than water systems in the same settlements.

We also found that secure waste management, particularly from septic tanks and pits, poses significant challenges for residents. Even when toilets can be found and functioning properly, there is often no secure and sustainable way to manage waste that accumulates in pits and tanks.

In many cases, sediment is dumped into open areas in the settlement, into local rivers, or seeps into the ground. This can contaminate water sources and create serious environmental and public health hazards.

In addition, we found that cyclones and heavy rains destroy sanitation systems, causing sewage to overflow and contaminating water resources.

Communities in danger

Water reservoir along the houses.
Waste management poses significant challenges.
Benny Zuse Rousso

Melanesian countries, including Vanuatu and Fiji, are particularly vulnerable to serious climatic hazardswhich makes it crucial that the sanitation infrastructure in informal urban settlements is able to withstand these environmental hazards.

Poor sanitary conditions in these areas leads to the spread diseases corresponding to diarrheaintestinal worms and trachoma. Studies show that improving water and sanitation systems significantly reduce the risk child deaths and deaths attributable to diarrhea.

Estimates from the World Health Organization and UNICEF indicate that lower than 3% urban population in Fiji and Vanuatu use unimproved or unsafe sanitation facilities – that is, facilities that do not allow for the secure collection, treatment and disposal of human waste.

This figure contrasts sharply with our finding that the majority of households in informal urban settlements depend on unsafe sanitation conditions. It highlights the need for improved monitoring strategies that distinguish informal settlements from formally planned areas.

How can we solve this problem?

Toilets alone won’t solve the problem. Communities need a comprehensive approach that addresses sanitation management at every stage. This will include creating a whole service chain that ensures reliable waste removal, treatment and disposal, and is resilient to disasters.

This means constructing local expertise, supporting local service providers, ensuring systems are well maintained and promoting community ownership of those systems to ensure long-term sustainability.

Outdoor toilet block, with view of mountain and trees in background.
We found that the majority of households in informal urban settlements profit from unsafe sanitation conditions.
Benny Zuse Rousso

In informal settlements, the provision of those services is rather more difficult than in formal urban areas, mainly due to the uncertain land tenure situation and limited access to adequate infrastructure, which makes the work of service providers difficult.

However, a significant slice of the urban population of the Pacific living in informal settlementsfinding effective ways to safely manage sanitation conditions in these communities is essential.

This sixth sustainable development goal goals to provide clean water and sanitation for all. Addressing the sanitation crisis in the Pacific Islands is about protecting health, restoring dignity, supporting livelihoods and constructing resilience at the household and community level, that are at the frontline of an increasingly uncertain future.

This article was originally published on : theconversation.com
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Health and Wellness

Herrana Addisu’s “River” Refers to Ethiopian Beauty Standards – Essence

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Courtesy of Kendall Bessent

What does visibility seem like? Growing up in Ethiopia, SheaMoisture Grant– Filmmaker and artist Herrana Addisu’s work is devoted to shedding light on women in conflict and wonder standards in her home country. This can also be the case in her latest film, supported by Tina Knowles. “[River is] “It’s a story that I’ve been writing in my head my whole life because it’s the foundation of my life and my livelihood as a child,” Addisu tells ESSENCE.

Herrana Addisu's 'River' Touches Ethiopian Beauty Standards

After winning the Blueprint Grant last August, SheaMoisture has taken on the role of a creative agency Chucha Studio to produce a movie that might bring to life a narrative that the black community could relate to. Focusing on culturally and politically sensitive topics—from access to water and education to ancestral lessons, forced marriages, and wonder standards—Adisu took the funds back to Ethiopia (to work with an area production house Dog Movies) tell her story.

“I wanted the film to have these complicated conversations that we don’t always have in this day and age,” she says. For example, Ethiopian stick-and-poke tattooing (often known as “Niksat”) is a typical tradition that runs through each of her pieces. “Growing up, I always thought it was beautiful,” she says. “But there’s a certain reluctance to do it, because a lot of women don’t feel like they’re consenting to have a permanent tattoo.”

Herrana Addisu's 'River' Touches Ethiopian Beauty Standards

Referencing cultural and traditional views of beauty, she cites spiritual icons of black hair within the church as a central theme. “Our old Bibles and paintings that I grew up seeing are of black angels and they have mini afros,” says Addisu, who placed them on the actors alongside cornrows, scarves and hairdos. “My blackness was so obvious to me that I wanted to show that in the film as well.”

Herrana Addisu's 'River' Touches Ethiopian Beauty Standards

But as an artist, she also embodies the sweetness she captures. After shooting in Ethiopia, Adisu returned to New York to take part in the series alongside .[Photographer] Kendall Bessant I had the concept to test my limits in doing this cone on my head,” she says. “It’s very easy to push those limits to a certain extent once you’re behind the lens after which in front of it.”

Herrana Addisu's 'River' Touches Ethiopian Beauty Standards

In one photo, she props her chin on a jewellery stand, her hair bouffant, and in one other, her curls are in front of a riverscape, alluding to the source of life within the film. “Water flows in the global South, especially in the rivers of Utopia, are very important not only in rural communities but also in urban ones,” she says.

But the river can also be a source of vulnerability for ladies, who’re exposed to violence, kidnapping and trafficking as they carry water. “I thought that was a powerful catalyst that brought the whole aspect of the film together.”

Herrana Addisu's 'River' Touches Ethiopian Beauty Standards


This article was originally published on : www.essence.com
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Health and Wellness

Why is pain so exhausting?

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One of essentially the most common feelings related to chronic pain is fatigue, which may grow to be overwhelming. People with chronic pain may report feeling lacking in energy and motivation to interact with others or the world around them.

In fact, a UK study of individuals with chronic health problems found that pain and fatigue were the 2 biggest barriers for an energetic and meaningful life.

But why is long-term pain so debilitating? One clue lies in the character of pain and its powerful influence on our thoughts and behaviors.

Short-term pain can protect you

Contemporary ways of fascinated by pain emphasize its protective properties—the way in which it grabs our attention and forces us to alter our behavior to be able to protect an element of our body.

Try this. Slowly pinch the skin. As you increase the pressure, you’ll notice that the feeling changes until it becomes painful. The pain is what keeps you from squeezing harder, right? It’s how pain protects us.

When we’re injured, tissue damage or inflammation makes our pain system more sensitive. This pain stops us from mechanically stressing the injured tissue while it heals. For example, the pain of a broken leg or a cut under the foot means we avoid walking on it.

The concept that “pain protects us and promotes healing” is one of the crucial vital things that folks with chronic pain tell us. they learned what helped them recuperate.

However, long-term pain can overprotect you

In the short term, pain serves an especially effective protective function, and the longer our pain system is energetic, the more protection it provides.

But persistent pain may also help us prevent recovery. People affected by pain call it “hypersensitivity of the pain system”. Think of your pain system as being on alert. And that is where exhaustion is available in.

When pain becomes an on a regular basis experience, triggered or reinforced by an ever-widening range of activities, contexts, and cues, it becomes a relentless drain on resources. Living with pain requires significant and sustained effort, and this makes us drained.

About 80% of us are lucky enough to not know what it’s wish to be in pain, day in and day trip, for months or years. But take a moment to assume what it’s like.

Imagine having to pay attention hard, gather energy, and use distraction techniques to finish on a regular basis activities, let alone work, caregiving, or other responsibilities.

Whenever you’re feeling pain, you’re faced with a selection of whether and tips on how to act. Continually making that selection requires thought, effort, and strategy.

Mentioning your pain or explaining its impact on every moment, task, or activity is also tiring and difficult to speak when nobody else sees or feels your pain. For those listening, it could grow to be tedious, exhausting, or distressing.

The concentration, energy gathering, and distraction techniques required could make on a regular basis life exhausting.
PRPicturesProduction/Shutterstock

No wonder the pain is exhausting

In chronic pain, it’s not only the pain system that’s on alert. Increased inflammation throughout the body (immune system on alert), impaired production of the hormone cortisol (endocrine system on alert), and stiff and cautious movements (motor system on alert) are also hand in hand with chronic pain.

Each of those contributes to fatigue and exhaustion. So learning to administer and resolve chronic pain often involves learning tips on how to best manage the overactivation of those systems.

Losing sleep is also factor each in fatigue and pain. Pain causes sleep disruption, and sleep loss contributes to pain.

In other words, chronic pain is rarely “just” pain. It’s no wonder that long-term pain can grow to be overwhelming and debilitating.

What actually works?

People who are suffering from chronic pain include: stigmatized, rejected AND misunderstoodwhich may result in them not getting the care they need. Ongoing pain can prevent people from working, limit their social contacts and affect their relationships. This can result in a downward spiral of social, personal and economic drawback.

That’s why we want higher access to evidence-based care and high-quality education for individuals with chronic pain.

There is excellent news, nevertheless. Modern chronic pain care, which is based on first gaining a contemporary understanding of the biology underlying chronic pain, it helps.

The key appears to be recognizing and accepting that a hypersensitive pain system plays a key role in chronic pain. This makes a fast fix highly unlikely, but a program of gradual change—perhaps over months and even years—holds promise.

Understanding how pain works, how chronic pain becomes overprotective, how our brain and body adapt to training, after which learning recent skills and techniques to steadily rewire each the brain and body offers hope based on science; there is a powerful supporting evidence With clinical trials.

Any support is helpful

The best treatments for chronic pain require effort, patience, persistence, courage, and infrequently a very good coach. All of this is a fairly overwhelming proposition for somebody who is already exhausted.

So in the event you are among the many 80% of the population that doesn’t suffer from chronic pain, take into consideration what is needed and support your colleague, friend, partner, child or parent on this journey.


This article was originally published on : theconversation.com
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