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Studies have shown that intermittent fasting can almost double the risk of dying from cardiovascular disease

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New research shows that a preferred weight reduction strategy that limits the hours at which calories are consumed can nearly double the long-term risk of death from cardiovascular disease, especially amongst individuals with cardiovascular disease or cancer.

But the query stays how time-restricted eating, which limits calorie intake to parts of the day, affects the risk of heart disease and stroke. Previous research has suggested that weight loss program can reduce cardiovascular risk aspects in the short term.

While latest research is compelling, the reasons participants selected this eating style are unknown, said Dr. Kenneth Mukamal, a primary care physician at Beth Israel Deaconess Medical Center and a professor of medicine at Harvard Medical School in Boston. Mukamal was not involved in the study, which was presented Monday at the American Heart Association’s Epidemiology, Prevention, Lifestyle and Cardiometabolic Health conference in Chicago.

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“It was a reasonable attempt to look at the long-term effects of time-restricted eating,” he said. “At first glance, this does not suggest that it would be beneficial to the cardiovascular system, in fact it was harmful. However, there may be health reasons to eat in a time-restricted way that makes it seem harmful when it is not.”

Mukamal said it’s too early to say that people should avoid time-restricted eating if it helps them achieve their weight reduction goals. “At this point, if people want to eat for shorter periods of time and it’s easier for them to maintain their weight that way, I wouldn’t use that as a reason not to do it,” he said.

Time-restricted eating, a sort of intermittent fasting, typically limits caloric intake to a window lasting 4 to 12 hours. Previous research has shown that it can be an efficient weight reduction strategy, especially when combined with calorie restriction. Research also suggests it can quickly lower blood pressure and other key markers of cardiovascular disease in obese people.

In the latest study, researchers analyzed dietary data from a nationwide survey of 20,078 U.S. adults with a mean age of 49. They recalled twice all the food and drinks that they had consumed in 24 hours.

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People who limited eating to lower than eight hours a day were almost twice as prone to die from cardiovascular disease, including heart disease and stroke, over a median follow-up of eight years, compared with those that ate meals . inside 12-16 hours. The eight-hour eating window was related to higher cardiovascular mortality in the general population, in addition to in individuals who had pre-existing cardiovascular disease or cancer.

Time-restricted eating doesn’t appear to have an effect on the risk of death from all causes combined, especially cancer. However, in individuals with cancer, eating greater than 16 hours a day was related to a lower risk of dying from cancer.

The results are considered preliminary until the full results are published in a peer-reviewed journal.

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Principal investigator Dr. Victor Wenze Zhong, professor and chair of epidemiology and biostatistics at the School of Public Health at Shanghai Jiao Tong University in China, said the findings surprised his team.

“Limiting daily eating time to a short period, such as eight hours, has gained popularity recently because it appears to help people lose weight and improve cardiometabolic health,” Zhong said. “We therefore expected that long-term adoption of eight-hour food restriction would be associated with a lower risk of cardiovascular death and even death from any cause. We were surprised to find out (it wasn’t true).”

Mukamal, nonetheless, said many aspects remain unexplained.

“It’s important to note that these are people who choose to eat this way,” he said, noting that it was an observational study, not a randomized one, by which people were asked to eat at different times for comparison. For example, individuals with cancer may struggle with loss of appetite and due to this fact eat for a shorter period of time, but their life expectancy could also be shorter.

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“Some of what seems harmful may be due to why people choose to eat this way,” Mukamal said.

However, even amongst people in the general population who selected to eat during restricted periods, “no clear cardiovascular benefits were found,” he said. “This leaves quite open the question of whether time-restricted eating can improve cardiovascular health in the long term.”

While research continues, people in search of healthier eating patterns should follow those proven to enhance heart health, Mukamal said. DASH (Dietary Approaches to Stop Hypertension), pescetarian and Mediterranean weight loss program scored highest for heart healthin line with the AHA scientific statement.

“At least for now, focusing on what people eat is more important than focusing on the time they eat,” Mukamal said.

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This article was originally published on : thegrio.com

Health and Wellness

The nasty norovirus returns fully with us, as the gastric virus increases

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Cases of the unlucky gastric worm According to government data, they grow in some parts of the United States.

The latest numbers from American control and disease prevention centers show 91 explosions Norovirus reported On December 5, in comparison with 69 explosions in the last week of November.

The numbers of the previous few years show a maximum of 65 epidemics reported in the first week of December.

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Norovirus infection is characterised by sudden vomiting and diarrhea. Explosions are sometimes visible on cruise ships, in the assembly of life situations, such as nursing and prison homes, as well as school AND Places where persons are close to one another.

Here are some things that it is advisable to find out about the virus.

What is norovirus?

According to CDC, norovirus is the fundamental reason for foods transmitted by food in the United States, accountable for 58% of such infections acquired annually.

Norovirus infections are brought on by a gaggle of viruses which are easily spreading, with only 10 viral particles have the ability to make someone sick, health experts say.

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About 2,500 Norovirus epidemics in the United States are reported in the United States. Explosions may occur throughout the yr, but most frequently occur from November to April.

Along with vomiting and diarrhea, typical symptoms include nausea, abdominal pain, body pain, headache and fever.

How do you understand this?

Most Norovirus epidemic occurs when people who find themselves already infected disseminate the virus into others by the use of direct means, for instance by sharing food or food vessels. Explosions may also be spread foodIN water or contaminated surfaces.

How long are you sick?

The disease brought on by Norovirus normally begins suddenly, and the symptoms arose from 12 to 48 hours after exposure to the virus. Most people change into higher in a single to a few days and can recuperate.

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However, from 19 to 21 million diseases annually in the United States, nonetheless, norovirus causes a median of 900 deaths and 109,000 hospitalizations per yr, mainly amongst adults aged 65 and older. This also results in 465,000 visits to the emergency department, mainly with young children.

Who is threatened?

People of all ages might be infected and get norovirus. Small children, elderly people and folks with a weakened immune system are the most threatened, and dehydration from vomiting and diarrhea are the most significant problem.

There are not any drugs for Norovirus treatment. Rehydration is really helpful to drink water and other liquids, aside from coffee, tea and alcohol.

Everyone who suffers from dehydration should seek medical help. Symptoms of dehydration include a discount in urination, dry mouth and throat as well as dizziness while standing. Dehydrated children might be extremely sleepy or picky and cry with a couple of tears or without them.

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How can I protect myself?

Strict and frequent washing of hands is the best defense against Norowirus in the peak winter season, scrubbing my hands with soap and warm water for 20 seconds before meals.

It also can assist in scrubbing surfaces with home disinfectants.

10 expert tips to help you change relationships with money in 2025

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This article was originally published on : thegrio.com
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Lela Rochon says that do not expect her to look as if she did it in the 90s at the age of 60

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60 -year -old Lela Rochon says:

(*60*)

Emma Mccintyre/Getty Images

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After selecting the priority of motherhood over movies and tv projects, actress Lel Rochon returns in front of the camera, where beauty belongs.

In case you miss him, Rochon was a guest Talk Show Sherri Shepherd where she promoted her latest series in which she produces and stars. But before immersion in the latest SHEPHERD program, he asked her a few classic project, which is 30 years old in 2025. When asked about the possibility of continuing, the actress said that one of them was in Whitney Houston, who played Savannah, died in 2012.

“We intended, but unfortunately Whitney passed, and then Fox has rights and intended to do it,” she said before she shared the direction that he thinks should go, specializing in the children that the heroes would have. “I thought it should apply to our children. And then we move inside, because the daughter I would have in the film would now be 30 years old. “After noticing that the film was made 30 years ago, Rochon decided to send a message to haters who had things to say about how it looks now compared to this, compared to this. “So everything you say:” It doesn’t look the same: “Don’t expect me to look the same!” She said. “30 years have passed.”

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For several years, people had something to say about her appearance when she was getting old, but she got here out actually, including Poppin on Instagram, looking like a fierce and wonderful sixtieth, when some last shots about beautiful ones were asked, Rochon joked: “Kudysz you give Hrements to something that he hates.”

As mentioned, Rochon went back after her hard -working profession after marrying the director Antoine Fuqua and starting a family. They have two children, Asia and Brando, students from the Civil Registry Office, and Fuqua has a son named Zachary from the previous relationship. When asked about her decision to determine the priorities of parenting, she said it was obvious.

“It was an easy choice because I tried to get pregnant, I tried to wear a child, so when it happened, I didn’t want to miss anything,” she said. “This is my best production.”

And as she said in Talk to American Urban Radio Networks At the Essence Festival of Culture last summer, taking this break was the best decision she could make. But now she is prepared to come back and get to work.

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“You can do everything, but not at once. I was one of those people who I do everything, but I didn’t really want to do it all. I decided not to do it all at once – she said. “I wanted to have my children, I wanted to raise my children, I wanted to be for them. I kept one foot in the door and one foot outside the entertainment door. And once I was ready to do more, I’m here. I’m outside, I do more. ”


This article was originally published on : www.essence.com
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Treatment of Parkinson’s disease and a restless leg syndrome is associated with risky behavior – this is what you need to know

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Headache and you feel that the disease is common uncomfortable side effects for a lot of drugs. Getting on to risky sexual or pathological gambling – not so common.

But BBC examination He emphasized that some drug treatment of the restless Parkinson syndrome can lead to such risky behavior.

Over 150,000 people in Great Britain Wish Parkinson’s – a state of degeneration that affects the brain. The important part of the damaged brain is an area that produces dopamine, a chemical relay that regulates movement. Less dopamine within the brain can lead to symptoms corresponding to trembling, muscle stiffness, slow movements and balance problems.

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Another movement disorder is Restless legs (RLS), which influences between 5% and 10% people in Great Britain, USA and Europe. Twice more women than men have RL amongst people over 35 years of age.



People from RL imagine that they’ve to uncontrolle their legs and can experience creeping, crawling or tingling in them. Usually the symptoms are worse at night, when dopamine levels are often lower. Although the precise cause of RLS is unknown, that was connected to genes underlying health conditions and dopamine imbalance.

One of the important methods of treating movement disorders is a group of drugs called Dopamine receptor agonistswhich include Cabergoline, Ropiniro, Bromocryptine and Pramipeksol. Dopamine receptor agonists increase the extent of dopamine within the brain and help regulate movement.

Dopamine is referred to as “Happy” hormone Because it is part of the brain prize system. When people do something funny or nice, dopamine is released of their brain. However, the use of agonist drugs of Dopamine-Receptor can raise these feelings, which leads to impulsive behavior.

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While common uncomfortable side effects include headaches, feeling illness and drowsiness, these drugs are also connected with a more odd side effect Impulse control disorders. They include risky sexual behavior (hypersexuality), pathological gambling, compulsive shopping and overeating. Hypersexuality It includes behaviors corresponding to a stronger than the same old need to have sexual intercourse or is unable to resist sexual effect, which could be harmful.

Previous reported cases Attach a 53-yr-old woman receiving Ropinirol and showing impulsive behaviors, corresponding to access to web pornography, using sex rooms, meeting strangers for sexual activity and compulsive shopping. Other thing He emphasized a 32-yr-old man who, after taking Ropinirol, began to get drunk with food and gambling, in order that he lost his savings.

When the medication was prescribed firstly of 2000, it was believed that impulse disorders were Rare side effect related to these drugs. But in 2007, regulatory agency for medicals and healthcare products (MHRA) Public assessment report He informed that “healthcare employees should warn patients that compulsive behavior of dopamine agonists may be associated with the dose.”

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Between 6% and 17% people from RLS who accept dopamine agonists develop some form of impulse control disorders, and at the identical time up to 20% People living from Parkinson can experience impulse control disorders.

But real numbers could be even higher, because many patients may not associate changes in behavior with the drug or could be too embarrassed to report it. Case reports Show that usually impulsive behavior stops when the medication is stopped.

Lawsuits

There are several individual and collective processes against pharmaceutical firms, including Glaxosmithklinewhich is produced by RECIP® (Ropiniro) and Pfizerwhich makes Cabaser® (Cabergoline). Patients undertaking actions against these firms claimed that they weren’t aware of these impulsive uncomfortable side effects.

For example, in 2012, a French court Ordered Glaxosmithkline to pay 160,000 kilos compensation for Didier Jambart, after he experienced “destructive effects” while taking Parkinson’s drug collecting. And in 2014, the Australian Federal Court approved the settlement against the Pfizer for a collective claim regarding Parkinson’s drug, Cabaser. 150 patients He claimed that they’d no warning in regards to the potential uncomfortable side effects-in this increased gambling, sex addiction and other high-risk classes-Cabaser.

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Currently, this is clearer within the patient’s information leaflets administered with all pharmaceuticals for movement disorders that some patients can have impulsive behavior.

In 2023, Mhra announced that it had increased Reports pathological gambling with a drug called Aripiprazole. This antipsychotic drug, used to treat schizophrenia and mania, partly acts as a dopamine receptor agonist.

Each drug that raises the extent of dopamine could theoretically associate with impulse control disorders and it is necessary that in such cases patient monitoring and their behavior.

Not everyone will experience uncomfortable side effects. Before starting any treatment, a doctor or pharmacist should explain potential uncomfortable side effects-but it surely is also necessary to read the data leaflet with any drug. And if you experience any impulsive behavior with these drugs, talk to your doctor or pharmacist immediately.

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This article was originally published on : theconversation.com
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